Verbal memory outcome in patients with normal preoperative verbal memory and left mesial temporal sclerosis

Anthony LoGalbo, Stephen Sawrie, David L Roth, Ruben Kuzniecky, Robert Knowlton, Edward Faught, Roy Martin

Research output: Contribution to journalArticle

Abstract

Purpose: Previous studies have shown that structural integrity (i.e., presence/absence of mesial temporal sclerosis (MTS)) of the left mesial temporal lobe is associated with verbal memory outcome following left anterior temporal lobectomy (ATL). However, the functional integrity of the left temporal lobe, as exemplified by preoperative verbal memory performance, has also been associated with verbal memory outcome following surgery. We investigated the risk of verbal memory loss in patients with known structural abnormality (i.e., left mesial temporal sclerosis by MRI) and normal preoperative verbal memory performance who undergo left ATL. Methods: Seventeen patients with left temporal lobe epilepsy, MRI-based exclusive left MTS, and normal preoperative verbal memory were identified. Normal verbal memory was defined as performance on both Acquisition (learning across trials 1-5) and Retrieval (long delayed free recall) portions of the California Verbal Learning Test (CVLT) above a T score of 40 (

Original languageEnglish (US)
Pages (from-to)337-341
Number of pages5
JournalEpilepsy and Behavior
Volume6
Issue number3
DOIs
StatePublished - May 2005
Externally publishedYes

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Sclerosis
Anterior Temporal Lobectomy
Temporal Lobe
Verbal Learning
Temporal Lobe Epilepsy
Memory Disorders
Learning

Keywords

  • Cognitive change
  • Memory
  • Mesial temporal sclerosis
  • Temporal lobe epilepsy

ASJC Scopus subject areas

  • Clinical Neurology
  • Behavioral Neuroscience
  • Neurology

Cite this

Verbal memory outcome in patients with normal preoperative verbal memory and left mesial temporal sclerosis. / LoGalbo, Anthony; Sawrie, Stephen; Roth, David L; Kuzniecky, Ruben; Knowlton, Robert; Faught, Edward; Martin, Roy.

In: Epilepsy and Behavior, Vol. 6, No. 3, 05.2005, p. 337-341.

Research output: Contribution to journalArticle

LoGalbo, Anthony ; Sawrie, Stephen ; Roth, David L ; Kuzniecky, Ruben ; Knowlton, Robert ; Faught, Edward ; Martin, Roy. / Verbal memory outcome in patients with normal preoperative verbal memory and left mesial temporal sclerosis. In: Epilepsy and Behavior. 2005 ; Vol. 6, No. 3. pp. 337-341.
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