Ventriculo-arterial coupling: Concepts, assumptions, and applications

David A. Kass, Raymond P. Kelly

Research output: Contribution to journalArticlepeer-review


Recent investigations have yielded new insights into the interaction of the left ventricle with the arterial system. These studies have employed a variety of coupling frameworks to quantify this interaction, and each makes several simplifying assumptions. In this article, we review these frameworks, their major findings, assumptions, and clinical applications, and examine future directions for this research.

Original languageEnglish (US)
Pages (from-to)41-62
Number of pages22
JournalAnnals of biomedical engineering
Issue number1
StatePublished - Jan 1992


  • Arterial impedance
  • Matching
  • Stroke work
  • Vascular load
  • Ventricular efficiency
  • Ventricular function
  • Ventricular pressure-volume relations

ASJC Scopus subject areas

  • Biomedical Engineering

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