Abstract
Arrhythmogenic right ventricular dysplasia/cardiomyopathy (ARVD/C) is a genetic cardiomyopathy characterized by ventricular arrhythmias and structural abnormalities of the right ventricle (RV). In ARVD/C there is progressive replacement of right ventricular myocardium with fatty and fibrous tissue. The precise prevalence of ARVD/C has been estimated to vary between 1 in 1000 and 1 in 5000 of the general population. The purpose of this chapter is to review the current understanding of ARVD/C and its management. Particular attention will be focused on some of the recent advances in the understanding of the genetic basis of ARVD/C and how this information provides insight into the mechanism of ventricular arrhythmias that can cause sudden death.
| Original language | English (US) |
|---|---|
| Title of host publication | Electrical Diseases of the Heart: Genetics, Mechanisms, Treatment, Prevention |
| Publisher | Springer London |
| Pages | 643-653 |
| Number of pages | 11 |
| ISBN (Print) | 9781846288531 |
| DOIs | |
| State | Published - 2008 |
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ASJC Scopus subject areas
- Medicine(all)
Cite this
Ventricular arrhythmias in right ventricular dysplasia/cardiomyopathy. / Calkins, Hugh; Marcus, Frank I.
Electrical Diseases of the Heart: Genetics, Mechanisms, Treatment, Prevention. Springer London, 2008. p. 643-653.Research output: Chapter in Book/Report/Conference proceeding › Chapter
}
TY - CHAP
T1 - Ventricular arrhythmias in right ventricular dysplasia/cardiomyopathy
AU - Calkins, Hugh
AU - Marcus, Frank I.
PY - 2008
Y1 - 2008
N2 - Arrhythmogenic right ventricular dysplasia/cardiomyopathy (ARVD/C) is a genetic cardiomyopathy characterized by ventricular arrhythmias and structural abnormalities of the right ventricle (RV). In ARVD/C there is progressive replacement of right ventricular myocardium with fatty and fibrous tissue. The precise prevalence of ARVD/C has been estimated to vary between 1 in 1000 and 1 in 5000 of the general population. The purpose of this chapter is to review the current understanding of ARVD/C and its management. Particular attention will be focused on some of the recent advances in the understanding of the genetic basis of ARVD/C and how this information provides insight into the mechanism of ventricular arrhythmias that can cause sudden death.
AB - Arrhythmogenic right ventricular dysplasia/cardiomyopathy (ARVD/C) is a genetic cardiomyopathy characterized by ventricular arrhythmias and structural abnormalities of the right ventricle (RV). In ARVD/C there is progressive replacement of right ventricular myocardium with fatty and fibrous tissue. The precise prevalence of ARVD/C has been estimated to vary between 1 in 1000 and 1 in 5000 of the general population. The purpose of this chapter is to review the current understanding of ARVD/C and its management. Particular attention will be focused on some of the recent advances in the understanding of the genetic basis of ARVD/C and how this information provides insight into the mechanism of ventricular arrhythmias that can cause sudden death.
UR - http://www.scopus.com/inward/record.url?scp=84890235507&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84890235507&partnerID=8YFLogxK
U2 - 10.1007/978-1-84628-854-8_45
DO - 10.1007/978-1-84628-854-8_45
M3 - Chapter
AN - SCOPUS:84890235507
SN - 9781846288531
SP - 643
EP - 653
BT - Electrical Diseases of the Heart: Genetics, Mechanisms, Treatment, Prevention
PB - Springer London
ER -