Abstract
Arrhythmogenic right ventricular dysplasia/cardiomyopathy (ARVD/C) is a genetic cardiomyopathy characterized by ventricular arrhythmias and structural abnormalities of the right ventricle (RV). In ARVD/C there is progressive replacement of right ventricular myocardium with fatty and fibrous tissue. The precise prevalence of ARVD/C has been estimated to vary between 1 in 1000 and 1 in 5000 of the general population. The purpose of this chapter is to review the current understanding of ARVD/C and its management. Particular attention will be focused on some of the recent advances in the understanding of the genetic basis of ARVD/C and how this information provides insight into the mechanism of ventricular arrhythmias that can cause sudden death.
Original language | English (US) |
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Title of host publication | Electrical Diseases of the Heart |
Subtitle of host publication | Genetics, Mechanisms, Treatment, Prevention |
Publisher | Springer London |
Pages | 643-653 |
Number of pages | 11 |
ISBN (Print) | 9781846288531 |
DOIs | |
State | Published - Dec 1 2008 |
ASJC Scopus subject areas
- Medicine(all)