Ventricular arrhythmias in cardiac sarcoidosis

David R. Okada, John Smith, Arsalan Derakhshan, Zain Gowani, Satish Misra, Ronald D. Berger, Hugh Calkins, Harikrishna Tandri, Jonathan Chrispin

Research output: Contribution to journalArticlepeer-review


The diagnosis of cardiac sarcoidosis (CS), especially in cases where there is limited or no extracardiac involvement, is challenging. Patients with CS are at increased risk of ventricular arrhythmias and sudden cardiac death. Several techniques for risk stratification for sudden cardiac death have been proposed in this population, including advanced cardiac imaging and electrophysiology study. Clinical ventricular arrhythmias in patients with CS may be treated with immunosuppressant therapy, antiarrhythmic drugs, catheter ablation, or implantable cardioverter-defibrillator placement. This article will provide an update on techniques for diagnosing CS, risk stratifying patients with CS for sudden cardiac death, and treating patients with CS with ventricular arrhythmias, focusing on evidence that has become available since publication of the 2014 Heart Rhythm Society Expert Consensus Statement on the Diagnosis and Management of Arrhythmias Associated With Cardiac Sarcoidosis.

Original languageEnglish (US)
Pages (from-to)1253-1264
Number of pages12
Issue number12
StatePublished - 2018


  • cardiac sarcoidosis
  • electrophysiology study
  • risk stratification
  • ventricular arrhythmias

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Physiology (medical)


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