Ventral and Dorsal Persistent Primitive Ophthalmic Arteries

Lydia Gregg, Diego San Millán, Emanuele Orru, Rafael J Tamargo, Philippe Gailloud

Research output: Contribution to journalArticle

Abstract

BACKGROUND:: Before the development of the adult ophthalmic artery (OA), the primitive maxillary artery (MA), the primitive dorsal OA, and the primitive ventral OA contribute to the vascularization of early ocular structures, whereas the primitive olfactory artery (OlfA) forms in the vicinity of the optic vesicle. These vessels are involved in several OA origin variants. OBJECTIVE:: To clarify the developmental history of the OA, emphasizing in particular the criteria used to define persistent primitive OAs. METHODS:: Eight rare variants relevant to the discussion of aberrant OA origins are presented. RESULTS:: Five abnormal anatomic configurations are described including (1) OAs branching from the cavernous internal carotid artery (ICA) involving a persistent primitive MA, (2) OAs originating from the distal supraclinoid ICA involving persistent primitive ventral or dorsal OAs, (3) an OA originating from the anterior cerebral artery (ACA) involving a persistent primitive OlfA, (4) a persistent primitive OlfA, and (5) infraoptic ACAs involving the persistent primitive MA, OlfA, and OA. CONCLUSION:: Discrepancies regarding the identification of persistent primitive OAs appear to result from a misinterpretation of the literature. Notably, an OA arising from the cavernous segment of the ICA derives from a primitive MA, whereas an OA arising from the ACA represents the partial persistence of a primitive OlfA; neither corresponds to a persistent primitive OA. Two new observations of this latter variant, which is exceptional, are presented. ABBREVIATIONS:: ACA, anterior cerebral arteryDSA, digital subtraction angiographyICA, internal carotid arteryILT, inferolateral trunkMA, maxillary arteryMMA, middle meningeal arteryMRA, magnetic resonance angiographyOA, ophthalmic arteryOlfA, olfactory arteryPComA, posterior communicating arterySOF, superior orbital fissure

Original languageEnglish (US)
JournalNeurosurgery
DOIs
StateAccepted/In press - Oct 19 2015

Fingerprint

Ophthalmic Artery
Maxillary Artery
Anterior Cerebral Artery
Arteries
Internal Carotid Artery
Magnetic Resonance Spectroscopy
History

ASJC Scopus subject areas

  • Clinical Neurology
  • Surgery

Cite this

Ventral and Dorsal Persistent Primitive Ophthalmic Arteries. / Gregg, Lydia; San Millán, Diego; Orru, Emanuele; Tamargo, Rafael J; Gailloud, Philippe.

In: Neurosurgery, 19.10.2015.

Research output: Contribution to journalArticle

@article{36eb0082cd874887947747f2d75abe93,
title = "Ventral and Dorsal Persistent Primitive Ophthalmic Arteries",
abstract = "BACKGROUND:: Before the development of the adult ophthalmic artery (OA), the primitive maxillary artery (MA), the primitive dorsal OA, and the primitive ventral OA contribute to the vascularization of early ocular structures, whereas the primitive olfactory artery (OlfA) forms in the vicinity of the optic vesicle. These vessels are involved in several OA origin variants. OBJECTIVE:: To clarify the developmental history of the OA, emphasizing in particular the criteria used to define persistent primitive OAs. METHODS:: Eight rare variants relevant to the discussion of aberrant OA origins are presented. RESULTS:: Five abnormal anatomic configurations are described including (1) OAs branching from the cavernous internal carotid artery (ICA) involving a persistent primitive MA, (2) OAs originating from the distal supraclinoid ICA involving persistent primitive ventral or dorsal OAs, (3) an OA originating from the anterior cerebral artery (ACA) involving a persistent primitive OlfA, (4) a persistent primitive OlfA, and (5) infraoptic ACAs involving the persistent primitive MA, OlfA, and OA. CONCLUSION:: Discrepancies regarding the identification of persistent primitive OAs appear to result from a misinterpretation of the literature. Notably, an OA arising from the cavernous segment of the ICA derives from a primitive MA, whereas an OA arising from the ACA represents the partial persistence of a primitive OlfA; neither corresponds to a persistent primitive OA. Two new observations of this latter variant, which is exceptional, are presented. ABBREVIATIONS:: ACA, anterior cerebral arteryDSA, digital subtraction angiographyICA, internal carotid arteryILT, inferolateral trunkMA, maxillary arteryMMA, middle meningeal arteryMRA, magnetic resonance angiographyOA, ophthalmic arteryOlfA, olfactory arteryPComA, posterior communicating arterySOF, superior orbital fissure",
author = "Lydia Gregg and {San Mill{\'a}n}, Diego and Emanuele Orru and Tamargo, {Rafael J} and Philippe Gailloud",
year = "2015",
month = "10",
day = "19",
doi = "10.1227/NEU.0000000000001066",
language = "English (US)",
journal = "Neurosurgery",
issn = "0148-396X",
publisher = "Lippincott Williams and Wilkins",

}

TY - JOUR

T1 - Ventral and Dorsal Persistent Primitive Ophthalmic Arteries

AU - Gregg, Lydia

AU - San Millán, Diego

AU - Orru, Emanuele

AU - Tamargo, Rafael J

AU - Gailloud, Philippe

PY - 2015/10/19

Y1 - 2015/10/19

N2 - BACKGROUND:: Before the development of the adult ophthalmic artery (OA), the primitive maxillary artery (MA), the primitive dorsal OA, and the primitive ventral OA contribute to the vascularization of early ocular structures, whereas the primitive olfactory artery (OlfA) forms in the vicinity of the optic vesicle. These vessels are involved in several OA origin variants. OBJECTIVE:: To clarify the developmental history of the OA, emphasizing in particular the criteria used to define persistent primitive OAs. METHODS:: Eight rare variants relevant to the discussion of aberrant OA origins are presented. RESULTS:: Five abnormal anatomic configurations are described including (1) OAs branching from the cavernous internal carotid artery (ICA) involving a persistent primitive MA, (2) OAs originating from the distal supraclinoid ICA involving persistent primitive ventral or dorsal OAs, (3) an OA originating from the anterior cerebral artery (ACA) involving a persistent primitive OlfA, (4) a persistent primitive OlfA, and (5) infraoptic ACAs involving the persistent primitive MA, OlfA, and OA. CONCLUSION:: Discrepancies regarding the identification of persistent primitive OAs appear to result from a misinterpretation of the literature. Notably, an OA arising from the cavernous segment of the ICA derives from a primitive MA, whereas an OA arising from the ACA represents the partial persistence of a primitive OlfA; neither corresponds to a persistent primitive OA. Two new observations of this latter variant, which is exceptional, are presented. ABBREVIATIONS:: ACA, anterior cerebral arteryDSA, digital subtraction angiographyICA, internal carotid arteryILT, inferolateral trunkMA, maxillary arteryMMA, middle meningeal arteryMRA, magnetic resonance angiographyOA, ophthalmic arteryOlfA, olfactory arteryPComA, posterior communicating arterySOF, superior orbital fissure

AB - BACKGROUND:: Before the development of the adult ophthalmic artery (OA), the primitive maxillary artery (MA), the primitive dorsal OA, and the primitive ventral OA contribute to the vascularization of early ocular structures, whereas the primitive olfactory artery (OlfA) forms in the vicinity of the optic vesicle. These vessels are involved in several OA origin variants. OBJECTIVE:: To clarify the developmental history of the OA, emphasizing in particular the criteria used to define persistent primitive OAs. METHODS:: Eight rare variants relevant to the discussion of aberrant OA origins are presented. RESULTS:: Five abnormal anatomic configurations are described including (1) OAs branching from the cavernous internal carotid artery (ICA) involving a persistent primitive MA, (2) OAs originating from the distal supraclinoid ICA involving persistent primitive ventral or dorsal OAs, (3) an OA originating from the anterior cerebral artery (ACA) involving a persistent primitive OlfA, (4) a persistent primitive OlfA, and (5) infraoptic ACAs involving the persistent primitive MA, OlfA, and OA. CONCLUSION:: Discrepancies regarding the identification of persistent primitive OAs appear to result from a misinterpretation of the literature. Notably, an OA arising from the cavernous segment of the ICA derives from a primitive MA, whereas an OA arising from the ACA represents the partial persistence of a primitive OlfA; neither corresponds to a persistent primitive OA. Two new observations of this latter variant, which is exceptional, are presented. ABBREVIATIONS:: ACA, anterior cerebral arteryDSA, digital subtraction angiographyICA, internal carotid arteryILT, inferolateral trunkMA, maxillary arteryMMA, middle meningeal arteryMRA, magnetic resonance angiographyOA, ophthalmic arteryOlfA, olfactory arteryPComA, posterior communicating arterySOF, superior orbital fissure

UR - http://www.scopus.com/inward/record.url?scp=84944768921&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84944768921&partnerID=8YFLogxK

U2 - 10.1227/NEU.0000000000001066

DO - 10.1227/NEU.0000000000001066

M3 - Article

JO - Neurosurgery

JF - Neurosurgery

SN - 0148-396X

ER -