TY - JOUR
T1 - Ventilatory responses to peripheral nerve stimulation at different times in the respiratory cycle
AU - Howard, Peter
AU - Bromberger-Barnea, Baruch
AU - Fitzgerald, Robert S.
AU - Bane, Harry N.
N1 - Funding Information:
Accepted for publication 30 May 1969. * Dorothy Temple Cross Travelling Scholar, Medical Research Council, London, England. Present address: The University of Sheffield, Department of Medicine, The Royal Hospital, Sheffield SI 3SR.
PY - 1969/10
Y1 - 1969/10
N2 - Discrete stimulation (40-500 msec duration) of the femoral nerve in the dog and the carotid sinus nerve of the cat was achieved at different moments during the respiratory cycle. Changes in tidal volume, respiratory rate and now pattern were measured. The response to stimulation varied according to the time in the cycle that the stimulus was given. Tidal volume and expiratory peak flow rate were usually reduced after stimulation in early inspiration but increased by the same stimulus in late inspiration or early expiration. Respiratory rate generally increased whatever time the stimulus was given. The pattern of response was broadly similar for the two nerves but there were important differences in detail.
AB - Discrete stimulation (40-500 msec duration) of the femoral nerve in the dog and the carotid sinus nerve of the cat was achieved at different moments during the respiratory cycle. Changes in tidal volume, respiratory rate and now pattern were measured. The response to stimulation varied according to the time in the cycle that the stimulus was given. Tidal volume and expiratory peak flow rate were usually reduced after stimulation in early inspiration but increased by the same stimulus in late inspiration or early expiration. Respiratory rate generally increased whatever time the stimulus was given. The pattern of response was broadly similar for the two nerves but there were important differences in detail.
KW - Breathing pattern
KW - Carotid sinus nerve
KW - Respiratory cycles
KW - Respiratory reflexes
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U2 - 10.1016/0034-5687(69)90022-x
DO - 10.1016/0034-5687(69)90022-x
M3 - Article
C2 - 5823845
AN - SCOPUS:0014594293
SN - 0034-5687
VL - 7
SP - 389
EP - 398
JO - Respiration Physiology
JF - Respiration Physiology
IS - 3
ER -