Vasoactive hormones in the pulmonary vascular bed

P. J. Kadowitz; E. W. Spannhake; D. S. Knight; A. L. Hyman

doi:10.1378/chest.71.2_supplement.257

Vasoactive hormones in the pulmonary vascular bed

P. J. Kadowitz, E. W. Spannhake, D. S. Knight, A. L. Hyman

Research output: Contribution to journal › Article › peer-review

6 Scopus citations

Abstract

In summary, results of the present studies show that arachidonic acid, PGE₂, PGF2α and an analog of the endoperoxide, PGH₂, are pressor substances in the canine pulmonary vascular bed. In addition, these studies show that the lung has marked capacity to synthesize vasoactive prostaglandins from arachidonic acid and that endoperoxides may represent a very active form of the prostaglandins in the pulmonary vascular bed.

Original language	English (US)
Pages (from-to)	257-261
Number of pages	5
Journal	CHEST
Volume	71
Issue number	2 . sup.
DOIs	https://doi.org/10.1378/chest.71.2_supplement.257
State	Published - 1977
Externally published	Yes

ASJC Scopus subject areas

Pulmonary and Respiratory Medicine
Critical Care and Intensive Care Medicine
Cardiology and Cardiovascular Medicine

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10.1378/chest.71.2_supplement.257

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title = "Vasoactive hormones in the pulmonary vascular bed",

abstract = "In summary, results of the present studies show that arachidonic acid, PGE2, PGF2α and an analog of the endoperoxide, PGH2, are pressor substances in the canine pulmonary vascular bed. In addition, these studies show that the lung has marked capacity to synthesize vasoactive prostaglandins from arachidonic acid and that endoperoxides may represent a very active form of the prostaglandins in the pulmonary vascular bed.",

author = "Kadowitz, {P. J.} and Spannhake, {E. W.} and Knight, {D. S.} and Hyman, {A. L.}",

note = "Funding Information: Supported by National Institutes of Health Grants HL 15580, HL 11802 and HL 18070. ",

year = "1977",

doi = "10.1378/chest.71.2_supplement.257",

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AU - Spannhake, E. W.

AU - Knight, D. S.

AU - Hyman, A. L.

N1 - Funding Information: Supported by National Institutes of Health Grants HL 15580, HL 11802 and HL 18070.

PY - 1977

Y1 - 1977

N2 - In summary, results of the present studies show that arachidonic acid, PGE2, PGF2α and an analog of the endoperoxide, PGH2, are pressor substances in the canine pulmonary vascular bed. In addition, these studies show that the lung has marked capacity to synthesize vasoactive prostaglandins from arachidonic acid and that endoperoxides may represent a very active form of the prostaglandins in the pulmonary vascular bed.

AB - In summary, results of the present studies show that arachidonic acid, PGE2, PGF2α and an analog of the endoperoxide, PGH2, are pressor substances in the canine pulmonary vascular bed. In addition, these studies show that the lung has marked capacity to synthesize vasoactive prostaglandins from arachidonic acid and that endoperoxides may represent a very active form of the prostaglandins in the pulmonary vascular bed.

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ER -

Vasoactive hormones in the pulmonary vascular bed

Abstract

ASJC Scopus subject areas

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