Vasoactive hormones in the pulmonary vascular bed

P. J. Kadowitz, E. W. Spannhake, D. S. Knight, A. L. Hyman

Research output: Contribution to journalArticlepeer-review

6 Scopus citations


In summary, results of the present studies show that arachidonic acid, PGE2, PGF2α and an analog of the endoperoxide, PGH2, are pressor substances in the canine pulmonary vascular bed. In addition, these studies show that the lung has marked capacity to synthesize vasoactive prostaglandins from arachidonic acid and that endoperoxides may represent a very active form of the prostaglandins in the pulmonary vascular bed.

Original languageEnglish (US)
Pages (from-to)257-261
Number of pages5
Issue number2 . sup.
StatePublished - 1977
Externally publishedYes

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine
  • Critical Care and Intensive Care Medicine
  • Cardiology and Cardiovascular Medicine


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