Variation of toxigenic Vibrio cholerae O1 in the aquatic environment of Bangladesh and its correlation with the clinical strains

Mohammad Sirajul Islam, Kaisar Ali Talukder, Nurul Huda Khan, Zahid Hayat Mahmud, Mohammed Ziaur Rahman, Gopinath Balakrish Nair, Abul K.M. Siddique, Mohammad Yunus, David Allen Sack, Richard Bradley Sack, Anwar Huq, Rita R. Colwell

Research output: Contribution to journalArticlepeer-review

Abstract

The diversity of toxigenic V. cholerae O1 in the aquatic environment of Bangladesh is not known. A total of 18 environmental and 18 clinical strains of toxigenic K cholerae O1 were isolated simultaneously from four different geographical areas and tested for variation by the pulsed-field gel electrophoresis method. Environmental strains showed diversified profiles and one of the profiles was common to some environmental strains and most clinical strains. It appears that one clone has an advantage over others to cause disease. These findings suggest that the study of the molecular ecology of V. cholerae O1 in relation to its environmental reservoir is important in identifying virulent strains that cause disease.

Original languageEnglish (US)
Pages (from-to)773-777
Number of pages5
JournalMicrobiology and Immunology
Volume48
Issue number10
DOIs
StatePublished - 2004

Keywords

  • Aquatic environment
  • Toxigenic variation
  • Vibrio cholerae O1

ASJC Scopus subject areas

  • Microbiology
  • Immunology
  • Virology

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