Variation of electrophoretic karyotypes among clinical isolates of Candida albicans

W. G. Merz, C. Connelly, P. Hieter

Research output: Contribution to journalArticlepeer-review


Orthogonal-field-alternation gel electrophoresis was used to compare clinical isolates of Candida albicans by resolving chromosome-sized DNA molecules into an electrophoretic karyotype. Seven to nine bands were observed among isolates recovered from 17 patients. In addition, 14 distinct electrophoretic patterns were noted among the isolates from these patients. In a given individual, isolates were likely to have identical electrophoretic patterns. Therefore, the electrophoretic karyotype patterns demonstrated by orthogonal-field-alternation gel electrophoresis can be used to designate a strain for epidemiologic studies.

Original languageEnglish (US)
Pages (from-to)842-845
Number of pages4
JournalJournal of clinical microbiology
Issue number5
StatePublished - 1988
Externally publishedYes

ASJC Scopus subject areas

  • Microbiology (medical)


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