Abstract
Most cases of gastric cancers occur in non-industrialized countries but there is scarce information about the epidemiology of this illness in these countries. Our study examined whether there was a variation in the prevalence of gastric cancer in Lima, Perú over the last 2 decades. Subjects older than 29 years of age were included. They underwent an esophagogastroduedonoscopy at 3 socioeconomically different health facilities in Lima: a county hospital (7,168 subjects), a Peruvian-Japanese Clinic (14,794 individuals) and a private hospital (4,893 individuals). Birth cohort prevalence of gastric cancer was used. Regression models were calculated to predict the future prevalence of gastric cancer. It was found that the birth cohort prevalence of gastric cancer decreased in Perú from 22.7 to 2% (p <0.001), from 12 to 0.5% (p <0.001), and from 6.5 to 0.1% (p <0.001) in the low, middle and high socioeconomic group, respectively. The prevalence of intestinal metaplasia decreased from 44.3 to 12.5% (p <0.001), from 28.4 to 5% (p <0.001), and from 19.4 to 2.2% (p <0.001) in the low, middle and high socioeconomic status, respectively. These trends will likely persist over the future decades. Nevertheless, the prevalence of gastric cancer remains high in subjects older than 59 years of age in the low socioeconomic status. It is concluded that the prevalence of gastric cancer is decreasing in Perú, similar to the current trend undergoing in industrialized nations. However, there are still specific groups with high prevalence that might benefit from screening for early detection and treatment.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 414-420 |
| Number of pages | 7 |
| Journal | International Journal of Cancer |
| Volume | 123 |
| Issue number | 2 |
| DOIs | |
| State | Published - Jul 15 2008 |
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Keywords
- Epidemiology
- Gastric cancer
- Intestinal metaplasia
ASJC Scopus subject areas
- Cancer Research
- Oncology
- Medicine(all)
Cite this
Variation in the prevalence of gastric cancer in Perú. / Mendoza, Daniel; Herrera, Phabiola; Gilman, Robert H; Lanfranco, Julio; Tapia, Martín; Bussalleu, Alejandro; Tenorio, Jorge Huerta Mercado; Guillén-Rodríguez, Carlos Enrique; Arróspide, Martín Tagle; Piscoya, Alejandro; Rosas-Aguirre, Angel; Watanabe-Yamamoto, José; Ferrufino, Juan Carlos; Scavino, Yolanda; Ramírez-Ramos, Alberto.
In: International Journal of Cancer, Vol. 123, No. 2, 15.07.2008, p. 414-420.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Variation in the prevalence of gastric cancer in Perú
AU - Mendoza, Daniel
AU - Herrera, Phabiola
AU - Gilman, Robert H
AU - Lanfranco, Julio
AU - Tapia, Martín
AU - Bussalleu, Alejandro
AU - Tenorio, Jorge Huerta Mercado
AU - Guillén-Rodríguez, Carlos Enrique
AU - Arróspide, Martín Tagle
AU - Piscoya, Alejandro
AU - Rosas-Aguirre, Angel
AU - Watanabe-Yamamoto, José
AU - Ferrufino, Juan Carlos
AU - Scavino, Yolanda
AU - Ramírez-Ramos, Alberto
PY - 2008/7/15
Y1 - 2008/7/15
N2 - Most cases of gastric cancers occur in non-industrialized countries but there is scarce information about the epidemiology of this illness in these countries. Our study examined whether there was a variation in the prevalence of gastric cancer in Lima, Perú over the last 2 decades. Subjects older than 29 years of age were included. They underwent an esophagogastroduedonoscopy at 3 socioeconomically different health facilities in Lima: a county hospital (7,168 subjects), a Peruvian-Japanese Clinic (14,794 individuals) and a private hospital (4,893 individuals). Birth cohort prevalence of gastric cancer was used. Regression models were calculated to predict the future prevalence of gastric cancer. It was found that the birth cohort prevalence of gastric cancer decreased in Perú from 22.7 to 2% (p <0.001), from 12 to 0.5% (p <0.001), and from 6.5 to 0.1% (p <0.001) in the low, middle and high socioeconomic group, respectively. The prevalence of intestinal metaplasia decreased from 44.3 to 12.5% (p <0.001), from 28.4 to 5% (p <0.001), and from 19.4 to 2.2% (p <0.001) in the low, middle and high socioeconomic status, respectively. These trends will likely persist over the future decades. Nevertheless, the prevalence of gastric cancer remains high in subjects older than 59 years of age in the low socioeconomic status. It is concluded that the prevalence of gastric cancer is decreasing in Perú, similar to the current trend undergoing in industrialized nations. However, there are still specific groups with high prevalence that might benefit from screening for early detection and treatment.
AB - Most cases of gastric cancers occur in non-industrialized countries but there is scarce information about the epidemiology of this illness in these countries. Our study examined whether there was a variation in the prevalence of gastric cancer in Lima, Perú over the last 2 decades. Subjects older than 29 years of age were included. They underwent an esophagogastroduedonoscopy at 3 socioeconomically different health facilities in Lima: a county hospital (7,168 subjects), a Peruvian-Japanese Clinic (14,794 individuals) and a private hospital (4,893 individuals). Birth cohort prevalence of gastric cancer was used. Regression models were calculated to predict the future prevalence of gastric cancer. It was found that the birth cohort prevalence of gastric cancer decreased in Perú from 22.7 to 2% (p <0.001), from 12 to 0.5% (p <0.001), and from 6.5 to 0.1% (p <0.001) in the low, middle and high socioeconomic group, respectively. The prevalence of intestinal metaplasia decreased from 44.3 to 12.5% (p <0.001), from 28.4 to 5% (p <0.001), and from 19.4 to 2.2% (p <0.001) in the low, middle and high socioeconomic status, respectively. These trends will likely persist over the future decades. Nevertheless, the prevalence of gastric cancer remains high in subjects older than 59 years of age in the low socioeconomic status. It is concluded that the prevalence of gastric cancer is decreasing in Perú, similar to the current trend undergoing in industrialized nations. However, there are still specific groups with high prevalence that might benefit from screening for early detection and treatment.
KW - Epidemiology
KW - Gastric cancer
KW - Intestinal metaplasia
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U2 - 10.1002/ijc.23420
DO - 10.1002/ijc.23420
M3 - Article
VL - 123
SP - 414
EP - 420
JO - International Journal of Cancer
JF - International Journal of Cancer
SN - 0020-7136
IS - 2
ER -