Variation in the duration of protection given by screening using the pap test for cervical cancer

Ann C. Klassen, David D. Celentano, Ron Brookmeyer

Research output: Contribution to journalArticlepeer-review

14 Scopus citations


The duration of protection offered by Pap screening for cervical cancer was examined using data on 101 cases of invasive cervical cancer and 396 controls from a Maryland case-control study. Receipt of a Pap test up to 4 years ago afforded significant protection, compared to women screened 1 I or more years ago, or never screened. Smoking, intercourse before age 19, and a history of sexually transmitted disease were significant risk factors for cervical cancer; barrier contraception use was protective. Variation in protection from Pap screening was examined by age, race, age at first intercourse, barrier contraception use, and source of last Pap test (obstetrician-gynecologist vs other provider type). Results showed older women, women with earlier age of first intercourse, and non-users of barrier contraception received slightly less protection from Pap tests, while women who received their last Pap test from an obstetrician-gynecologist received significantly more protection than women who did not. Issues of quality of screening and follow-up are discussed in regard to these results.

Original languageEnglish (US)
Pages (from-to)1003-1011
Number of pages9
JournalJournal of Clinical Epidemiology
Issue number10
StatePublished - 1989


  • Cervical cancer
  • Length of protection
  • Pap screening

ASJC Scopus subject areas

  • Epidemiology


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