Variability of heart rate, P-R, QRS and Q-T durations in twins

Richard J. Havlik; Robert J. Garrison; Richard Fabsitz; Manning Feinleib

doi:10.1016/S0022-0736(80)80008-2

Variability of heart rate, P-R, QRS and Q-T durations in twins

Richard J. Havlik, Robert J. Garrison, Richard Fabsitz, Manning Feinleib

Research output: Contribution to journal › Article

Abstract

During a cardiovascular risk factor study, electrocardiograms were done on 355 sets of middle-aged male monozygotic and dizygotic twins. Potential genetic variability in ventricular rate and P-R, QRS, and Q-T duration was investigated using classical statistical twin methodology. Significant genetically determined variability was found for ventricular rate and P-R interval. These findings suggest that heart rate and, to a lesser extent, atrial depolarization are under genetic control with 54% and 34%, respectively, of the variation among individuals explained by heredity.

Original language	English (US)
Pages (from-to)	45-48
Number of pages	4
Journal	Journal of Electrocardiology
Volume	13
Issue number	1
DOIs	https://doi.org/10.1016/S0022-0736(80)80008-2
State	Published - 1980
Externally published	Yes

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ASJC Scopus subject areas

Cardiology and Cardiovascular Medicine

Cite this

Havlik, R. J., Garrison, R. J., Fabsitz, R., & Feinleib, M. (1980). Variability of heart rate, P-R, QRS and Q-T durations in twins. Journal of Electrocardiology, 13(1), 45-48. https://doi.org/10.1016/S0022-0736(80)80008-2

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AB - During a cardiovascular risk factor study, electrocardiograms were done on 355 sets of middle-aged male monozygotic and dizygotic twins. Potential genetic variability in ventricular rate and P-R, QRS, and Q-T duration was investigated using classical statistical twin methodology. Significant genetically determined variability was found for ventricular rate and P-R interval. These findings suggest that heart rate and, to a lesser extent, atrial depolarization are under genetic control with 54% and 34%, respectively, of the variation among individuals explained by heredity.

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10.1016/S0022-0736(80)80008-2