Variability of defibrillation threshold in HEARTSIM: A 3D computer model of the heart

N. Thakor, R. Province, M. Fishler, R. Chen

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

The authors present a three-dimensional computer model of the heart to demonstrate simulation of ventricular fibrillation (VF) and defibrillation (DF). Delivery of a run of extra-stimuli initiated self-sustaining rapid regular rhythm or coarse and fine VF. Shocks of increasing strengths were applied at various times to determine the energy required for successful DF. The success rate curve versus DF energy showed the expected sigmoidal shape. For a given episode, the energy required for DF showed remarkable variation from moment to moment. Two successive pulses significantly lowered the energy requirement. The optimum interval between pulses was found to center around 85 ms, and the energy for the second pulse was lower than that for the first pulse. A biphasic pulse also lowered the energy requirement.

Original languageEnglish (US)
Title of host publicationComputers in Cardiology
PublisherPubl by IEEE
Pages209-212
Number of pages4
ISBN (Print)081862485X
StatePublished - Jan 1 1992
Externally publishedYes
EventProceedings of the 18th Annual Conference on Computers in Cardiology - Venice, Italy
Duration: Sep 23 1991Sep 26 1991

Publication series

NameComputers in Cardiology
ISSN (Print)0276-6574

Other

OtherProceedings of the 18th Annual Conference on Computers in Cardiology
CityVenice, Italy
Period9/23/919/26/91

ASJC Scopus subject areas

  • Computer Science Applications
  • Cardiology and Cardiovascular Medicine

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