Variability in immunization guidelines in children before and after lung transplantation

Christian Benden, Lara A. Danziger-Isakov, Todd Astor, Paul Aurora, Katharina Bluemchen, Debra Boyer, Carol Conrad, Irmgard Eichler, Okan Elidemir, Samuel Goldfarb, Marian G. Michaels, Peter J. Mogayzel, Carsten Mueller, Daiva Parakininkas, Donna Oberkfell, Melinda Solomon, Annette Boehler

Research output: Contribution to journalReview articlepeer-review

Abstract

Lung transplant candidates and recipients are at high risk of infections from vaccine-preventable diseases. However, well-established guidelines neither exist for pre- and post-transplant vaccination nor do monitoring guidelines for pediatric lung transplant recipients. To ascertain the current vaccination and monitoring practices of pediatric lung transplant centers, a self-administered questionnaire was distributed to the 18 pediatric lung transplant centers within the International Pediatric Lung Transplant Collaborative in April 2006. Sixteen of 18 centers (89%) surveyed responded. Pretransplant, national vaccination guidelines are followed. Eleven centers reported following standardized vaccination guidelines post-transplant. Vaccines were more commonly provided by the primary-care physician pretransplant (69%) rather than post-transplant (38%). Post-transplant, 50% of the centers recommend live vaccines for household contacts but not for the transplant recipient. Pretransplant monitoring of response to prior vaccination was performed inconsistently except for varicella (88%). Only 44% of the transplant centers measure for response to vaccination post-transplant, mostly hepatitis B. Current vaccination practices of pediatric lung transplant centers are heterogeneous. The lung transplant community would be well served by studies designed to evaluate the efficacy of vaccinations in this population.

Original languageEnglish (US)
Pages (from-to)882-887
Number of pages6
JournalPediatric transplantation
Volume11
Issue number8
DOIs
StatePublished - Dec 2007

Keywords

  • Immunization
  • Lung transplantation
  • Pediatrics
  • Solid organ transplantation
  • Vaccine response

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Transplantation

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