Variability in cyst fluid carcinoembryonic antigen level, fluid viscosity, amylase content, and cytologic findings among multiple loculi of a pancreatic mucinous cystic neoplasm

K. B. Lewandrowski, A. L. Warshaw, C. C. Compton, M. R. Pins, J. F. Southern

Research output: Contribution to journalArticle

Abstract

The procedure of percutaneous aspiration and analysis of cyst contents has been advocated to provide a preoperative diagnosis of pancreatic cystic lesions (pseudocysts and cystic tumors), but it is not known whether variation in the contents of separate loculi of a multilocular neoplasm might misrepresent the identity of the tumor. The authors measured the cyst fluid carcinoembryonic antigen (CEA) level, fluid viscosity, and amylase content and performed cytologic analysis on aspirates from ten different loculi of a single mucinous cystic neoplasm of the pancreas. The CEA levels were highly variable (median, 6,326 ng/mL; range, 962-64,670 ng/mL) but in all cases were diagnostic of a mucinous tumor. Fluid relative viscosity values were also variable (median, 2.4; range, 1.3-10+) but diagnostic in eight of nine aspirates. The amylase content in all of the loculi was low (

Original languageEnglish (US)
Pages (from-to)425-427
Number of pages3
JournalAmerican Journal of Clinical Pathology
Volume100
Issue number4
StatePublished - 1993
Externally publishedYes

Fingerprint

Cyst Fluid
Carcinoembryonic Antigen
Amylases
Viscosity
Neoplasms
Pancreatic Neoplasms
Cysts

Keywords

  • Borderline tumors
  • Fine-needle aspiration
  • Pancreatic neoplasms

ASJC Scopus subject areas

  • Pathology and Forensic Medicine

Cite this

Variability in cyst fluid carcinoembryonic antigen level, fluid viscosity, amylase content, and cytologic findings among multiple loculi of a pancreatic mucinous cystic neoplasm. / Lewandrowski, K. B.; Warshaw, A. L.; Compton, C. C.; Pins, M. R.; Southern, J. F.

In: American Journal of Clinical Pathology, Vol. 100, No. 4, 1993, p. 425-427.

Research output: Contribution to journalArticle

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AU - Lewandrowski, K. B.

AU - Warshaw, A. L.

AU - Compton, C. C.

AU - Pins, M. R.

AU - Southern, J. F.

PY - 1993

Y1 - 1993

N2 - The procedure of percutaneous aspiration and analysis of cyst contents has been advocated to provide a preoperative diagnosis of pancreatic cystic lesions (pseudocysts and cystic tumors), but it is not known whether variation in the contents of separate loculi of a multilocular neoplasm might misrepresent the identity of the tumor. The authors measured the cyst fluid carcinoembryonic antigen (CEA) level, fluid viscosity, and amylase content and performed cytologic analysis on aspirates from ten different loculi of a single mucinous cystic neoplasm of the pancreas. The CEA levels were highly variable (median, 6,326 ng/mL; range, 962-64,670 ng/mL) but in all cases were diagnostic of a mucinous tumor. Fluid relative viscosity values were also variable (median, 2.4; range, 1.3-10+) but diagnostic in eight of nine aspirates. The amylase content in all of the loculi was low (

AB - The procedure of percutaneous aspiration and analysis of cyst contents has been advocated to provide a preoperative diagnosis of pancreatic cystic lesions (pseudocysts and cystic tumors), but it is not known whether variation in the contents of separate loculi of a multilocular neoplasm might misrepresent the identity of the tumor. The authors measured the cyst fluid carcinoembryonic antigen (CEA) level, fluid viscosity, and amylase content and performed cytologic analysis on aspirates from ten different loculi of a single mucinous cystic neoplasm of the pancreas. The CEA levels were highly variable (median, 6,326 ng/mL; range, 962-64,670 ng/mL) but in all cases were diagnostic of a mucinous tumor. Fluid relative viscosity values were also variable (median, 2.4; range, 1.3-10+) but diagnostic in eight of nine aspirates. The amylase content in all of the loculi was low (

KW - Borderline tumors

KW - Fine-needle aspiration

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