Vanilloid receptors take a TRP beyond the sensory afferent

Research output: Contribution to journalReview articlepeer-review

78 Scopus citations


TRPV1 expression extends to a number of cells besides cutaneous afferents, suggesting functions for this molecule in diverse sensory and non-sensory processes. Possible side effects related to visceral, thermoregulatory, cognitive, motor, or emotional functions must therefore be considered during the development of therapeutic strategies involving the systemic administration of agents active at TRPV1. Proper dosing and biodistribution will undoubtedly be critical parameters in these strategies, as in others aimed at molecules presumed to be 'nociceptor-specific'.

Original languageEnglish (US)
Pages (from-to)5-9
Number of pages5
Issue number1-2
StatePublished - Sep 2003

ASJC Scopus subject areas

  • Neurology
  • Clinical Neurology
  • Anesthesiology and Pain Medicine


Dive into the research topics of 'Vanilloid receptors take a TRP beyond the sensory afferent'. Together they form a unique fingerprint.

Cite this