Abstract
Among women with valvular heart disease, those with mitral stenosis carry the greatest potential for problems during pregnancy. Asymptomatic women with aortic stenosis and only mild or moderate left ventricular outflow obstruction generally tolerate pregnancy well, as do those with regurgitant lesions. In Marfan syndrome, pregnancy should not be undertaken if the aortic root dimension exceeds 4 cm. Even if the aortic root is normal, a small increased risk of dissection is present. Women with well-functioning bioprosthetic valves and normal hemodynamics may safely undertake a pregnancy, although bioprostheses deteriorate rapidly in young people.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 369-381 |
| Number of pages | 13 |
| Journal | Cardiology Clinics |
| Volume | 30 |
| Issue number | 3 |
| DOIs | |
| State | Published - Aug 2012 |
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Keywords
- Bicuspid aortic valve
- Hypertrophic cardiomyopathy
- Marfan syndrome
- Mitral stenosis
- Pregnancy
- Prosthetic heart valves
ASJC Scopus subject areas
- Cardiology and Cardiovascular Medicine
Cite this
Valvular Heart Disease and Pregnancy. / Traill, Thomas A.
In: Cardiology Clinics, Vol. 30, No. 3, 08.2012, p. 369-381.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Valvular Heart Disease and Pregnancy
AU - Traill, Thomas A
PY - 2012/8
Y1 - 2012/8
N2 - Among women with valvular heart disease, those with mitral stenosis carry the greatest potential for problems during pregnancy. Asymptomatic women with aortic stenosis and only mild or moderate left ventricular outflow obstruction generally tolerate pregnancy well, as do those with regurgitant lesions. In Marfan syndrome, pregnancy should not be undertaken if the aortic root dimension exceeds 4 cm. Even if the aortic root is normal, a small increased risk of dissection is present. Women with well-functioning bioprosthetic valves and normal hemodynamics may safely undertake a pregnancy, although bioprostheses deteriorate rapidly in young people.
AB - Among women with valvular heart disease, those with mitral stenosis carry the greatest potential for problems during pregnancy. Asymptomatic women with aortic stenosis and only mild or moderate left ventricular outflow obstruction generally tolerate pregnancy well, as do those with regurgitant lesions. In Marfan syndrome, pregnancy should not be undertaken if the aortic root dimension exceeds 4 cm. Even if the aortic root is normal, a small increased risk of dissection is present. Women with well-functioning bioprosthetic valves and normal hemodynamics may safely undertake a pregnancy, although bioprostheses deteriorate rapidly in young people.
KW - Bicuspid aortic valve
KW - Hypertrophic cardiomyopathy
KW - Marfan syndrome
KW - Mitral stenosis
KW - Pregnancy
KW - Prosthetic heart valves
UR - http://www.scopus.com/inward/record.url?scp=84863874037&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84863874037&partnerID=8YFLogxK
U2 - 10.1016/j.ccl.2012.04.004
DO - 10.1016/j.ccl.2012.04.004
M3 - Article
C2 - 22813363
AN - SCOPUS:84863874037
VL - 30
SP - 369
EP - 381
JO - Cardiology Clinics
JF - Cardiology Clinics
SN - 0733-8651
IS - 3
ER -