Value of fluorodeoxyglucose PET/computed tomography patient management and outcomes in thyroid cancer

Anthony Ciarallo; Charles Marcus; Mehdi Taghipour; Rathan M. Subramaniam

doi:10.1016/j.cpet.2014.12.009

Value of fluorodeoxyglucose PET/computed tomography patient management and outcomes in thyroid cancer

Anthony Ciarallo, Charles Marcus, Mehdi Taghipour, Rathan M. Subramaniam

School of Medicine

Research output: Contribution to journal › Review article › peer-review

16 Scopus citations

Abstract

"Fluorodeoxyglucose (FDG) PET/computed tomography (CT) is used most frequently in the surveillance of iodine-refractory differentiated thyroid cancer with increased thyroglobulin level after therapy. This article evaluates the impact of FDG-PET/CT on clinical management and the prognostic implications of a positive scan. In the studies reviewed, FDG-PET/CT changed the course of management in 14% to 78% of patients with suspected recurrence, and a positive scan was associated with poorer survival. Similar conclusions are supported in the literature for anaplastic and medullary thyroid cancers, although these are based on fewer studies on account of the lower prevalence of these subtypes."

Original language	English (US)
Pages (from-to)	265-278
Number of pages	14
Journal	PET Clinics
Volume	10
Issue number	2
DOIs	https://doi.org/10.1016/j.cpet.2014.12.009
State	Published - Apr 1 2015

Keywords

FDG
Outcome
PET/CT
Prognosis
Thyroid cancer

ASJC Scopus subject areas

Radiation
Radiology Nuclear Medicine and imaging

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10.1016/j.cpet.2014.12.009

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title = "Value of fluorodeoxyglucose PET/computed tomography patient management and outcomes in thyroid cancer",

abstract = "{"}Fluorodeoxyglucose (FDG) PET/computed tomography (CT) is used most frequently in the surveillance of iodine-refractory differentiated thyroid cancer with increased thyroglobulin level after therapy. This article evaluates the impact of FDG-PET/CT on clinical management and the prognostic implications of a positive scan. In the studies reviewed, FDG-PET/CT changed the course of management in 14% to 78% of patients with suspected recurrence, and a positive scan was associated with poorer survival. Similar conclusions are supported in the literature for anaplastic and medullary thyroid cancers, although these are based on fewer studies on account of the lower prevalence of these subtypes.{"}",

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T1 - Value of fluorodeoxyglucose PET/computed tomography patient management and outcomes in thyroid cancer

AU - Ciarallo, Anthony

AU - Marcus, Charles

AU - Taghipour, Mehdi

AU - Subramaniam, Rathan M.

PY - 2015/4/1

Y1 - 2015/4/1

N2 - "Fluorodeoxyglucose (FDG) PET/computed tomography (CT) is used most frequently in the surveillance of iodine-refractory differentiated thyroid cancer with increased thyroglobulin level after therapy. This article evaluates the impact of FDG-PET/CT on clinical management and the prognostic implications of a positive scan. In the studies reviewed, FDG-PET/CT changed the course of management in 14% to 78% of patients with suspected recurrence, and a positive scan was associated with poorer survival. Similar conclusions are supported in the literature for anaplastic and medullary thyroid cancers, although these are based on fewer studies on account of the lower prevalence of these subtypes."

AB - "Fluorodeoxyglucose (FDG) PET/computed tomography (CT) is used most frequently in the surveillance of iodine-refractory differentiated thyroid cancer with increased thyroglobulin level after therapy. This article evaluates the impact of FDG-PET/CT on clinical management and the prognostic implications of a positive scan. In the studies reviewed, FDG-PET/CT changed the course of management in 14% to 78% of patients with suspected recurrence, and a positive scan was associated with poorer survival. Similar conclusions are supported in the literature for anaplastic and medullary thyroid cancers, although these are based on fewer studies on account of the lower prevalence of these subtypes."

KW - FDG

KW - Outcome

KW - PET/CT

KW - Prognosis

KW - Thyroid cancer

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Value of fluorodeoxyglucose PET/computed tomography patient management and outcomes in thyroid cancer

Abstract

Keywords

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