Valproate for the treatment of medication-induced impulse-control disorders in three patients with Parkinson's disease

C. W. Hicks, M. M. Pandya, I. Itin, H. H. Fernandez

Research output: Contribution to journalArticlepeer-review

Abstract

Impulse-control disorders (ICDs) are becoming more commonly recognized in the Parkinson disease (PD) population. To date, there are no definitive methods of treating dopamine dysregulation syndromes in PD patients. We sought to uncover an effective treatment option for future study. We report a series of 3 PD patients with ICDs who were effectively treated with valproate. Based on these encouraging preliminary observations, future controlled clinical trials investigating the efficacy of valproate for ICDs in PD are recommended.

Original languageEnglish (US)
Pages (from-to)379-381
Number of pages3
JournalParkinsonism and Related Disorders
Volume17
Issue number5
DOIs
StatePublished - Jun 2011
Externally publishedYes

Keywords

  • Dopamine dysregulation
  • Impulse-control disorder
  • Parkinson's disease
  • Valproate

ASJC Scopus subject areas

  • Neurology
  • Geriatrics and Gerontology
  • Clinical Neurology

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