Validity of the Cornell scale for depression in Dementia in Parkinson's disease with and without cognitive impairment

James R. Williams, Laura Marsh

Research output: Contribution to journalArticle

Abstract

Valid tools are needed to assess depression across the spectrum of cognitive impairment in Parkinson's disease (PD). The validity of the Cornell scale for depression in dementia (CSDD) was tested in a PD sample with a range of cognitive impairment. Psychiatric diagnoses were established according to DSM-IV-TR. Receiver operating characteristic curves tested the discriminant validity of the CSDD compared to the clinical diagnoses of major and minor depression. The curve for symptomatic depression had an area under the curve of 0.82. For the cut-off score ≥ 6, sensitivity was 0.83 and specificity was 0.73; for the cut-off score ≥ 8, sensitivity was 0.75 and specificity was 0.82. There was no evidence for differential measurement with respect to cognitive impairment or any other demographic or clinical variables. This study suggests that the CSDD is a valid tool for identifying depressive disorders in patients with PD across a spectrum of cognitive impairment.

Original languageEnglish (US)
Pages (from-to)433-437
Number of pages5
JournalMovement disorders : official journal of the Movement Disorder Society
Volume24
Issue number3
DOIs
StatePublished - Feb 15 2009

Keywords

  • Cognition
  • Cornell scale
  • Dementia
  • Depression
  • Parkinson's disease
  • Rating scale

ASJC Scopus subject areas

  • Clinical Neurology
  • Neurology
  • Medicine(all)

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