Abstract
Valid tools are needed to assess depression across the spectrum of cognitive impairment in Parkinson's disease (PD). The validity of the Cornell scale for depression in dementia (CSDD) was tested in a PD sample with a range of cognitive impairment. Psychiatric diagnoses were established according to DSM-IV-TR. Receiver operating characteristic curves tested the discriminant validity of the CSDD compared to the clinical diagnoses of major and minor depression. The curve for symptomatic depression had an area under the curve of 0.82. For the cut-off score ≥ 6, sensitivity was 0.83 and specificity was 0.73; for the cut-off score ≥ 8, sensitivity was 0.75 and specificity was 0.82. There was no evidence for differential measurement with respect to cognitive impairment or any other demographic or clinical variables. This study suggests that the CSDD is a valid tool for identifying depressive disorders in patients with PD across a spectrum of cognitive impairment.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 433-437 |
| Number of pages | 5 |
| Journal | Movement disorders : official journal of the Movement Disorder Society |
| Volume | 24 |
| Issue number | 3 |
| DOIs | |
| State | Published - Feb 15 2009 |
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Keywords
- Cognition
- Cornell scale
- Dementia
- Depression
- Parkinson's disease
- Rating scale
ASJC Scopus subject areas
- Clinical Neurology
- Neurology
- Medicine(all)
Cite this
Validity of the Cornell scale for depression in Dementia in Parkinson's disease with and without cognitive impairment. / Williams, James R.; Marsh, Laura.
In: Movement disorders : official journal of the Movement Disorder Society, Vol. 24, No. 3, 15.02.2009, p. 433-437.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Validity of the Cornell scale for depression in Dementia in Parkinson's disease with and without cognitive impairment
AU - Williams, James R.
AU - Marsh, Laura
PY - 2009/2/15
Y1 - 2009/2/15
N2 - Valid tools are needed to assess depression across the spectrum of cognitive impairment in Parkinson's disease (PD). The validity of the Cornell scale for depression in dementia (CSDD) was tested in a PD sample with a range of cognitive impairment. Psychiatric diagnoses were established according to DSM-IV-TR. Receiver operating characteristic curves tested the discriminant validity of the CSDD compared to the clinical diagnoses of major and minor depression. The curve for symptomatic depression had an area under the curve of 0.82. For the cut-off score ≥ 6, sensitivity was 0.83 and specificity was 0.73; for the cut-off score ≥ 8, sensitivity was 0.75 and specificity was 0.82. There was no evidence for differential measurement with respect to cognitive impairment or any other demographic or clinical variables. This study suggests that the CSDD is a valid tool for identifying depressive disorders in patients with PD across a spectrum of cognitive impairment.
AB - Valid tools are needed to assess depression across the spectrum of cognitive impairment in Parkinson's disease (PD). The validity of the Cornell scale for depression in dementia (CSDD) was tested in a PD sample with a range of cognitive impairment. Psychiatric diagnoses were established according to DSM-IV-TR. Receiver operating characteristic curves tested the discriminant validity of the CSDD compared to the clinical diagnoses of major and minor depression. The curve for symptomatic depression had an area under the curve of 0.82. For the cut-off score ≥ 6, sensitivity was 0.83 and specificity was 0.73; for the cut-off score ≥ 8, sensitivity was 0.75 and specificity was 0.82. There was no evidence for differential measurement with respect to cognitive impairment or any other demographic or clinical variables. This study suggests that the CSDD is a valid tool for identifying depressive disorders in patients with PD across a spectrum of cognitive impairment.
KW - Cognition
KW - Cornell scale
KW - Dementia
KW - Depression
KW - Parkinson's disease
KW - Rating scale
UR - http://www.scopus.com/inward/record.url?scp=67651083821&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=67651083821&partnerID=8YFLogxK
U2 - 10.1002/mds.22421
DO - 10.1002/mds.22421
M3 - Article
C2 - 19117358
AN - SCOPUS:67651083821
VL - 24
SP - 433
EP - 437
JO - Movement Disorders
JF - Movement Disorders
SN - 0885-3185
IS - 3
ER -