TY - JOUR
T1 - Validation of a Simplified Method to Determine Left Atrial Volume by Computed Tomography in Patients With Atrial Fibrillation
AU - Hof, Irene
AU - Arbab-Zadeh, Armin
AU - Dong, Jun
AU - Scherr, Daniel
AU - Chilukuri, Karuna
AU - Calkins, Hugh
N1 - Funding Information:
Irene Hof was supported by the Trajectum Fund, Utrecht, The Netherlands; the Wijck-Stam-Caspers Fund, Utrecht, The Netherlands; and the Hendrik Muller's Vaderlandsch Fund (The Hague, The Netherlands). Dr. Chilukuri was supported by the Norbert and Louise Grunwald Cardiac Arrhythmia Research Fund (Baltimore, Maryland). Dr. Scherr was supported by the Austrian Science Fund (Vienna, Austria).
Copyright:
Copyright 2009 Elsevier B.V., All rights reserved.
PY - 2008/12/1
Y1 - 2008/12/1
N2 - The success of catheter ablation of atrial fibrillation (AF) is highly dependent on a preprocedural assessment of the size and shape of the left atrium. The most precise method to determine left atrial (LA) volume using computed tomography requires manually tracing the LA area of each cross-sectional image. This is a labor-intensive and time-consuming technique. The purpose of this study was to compare LA volume derived using the "gold-standard" multiple-slice technique with LA volume estimated using 3 orthogonal LA dimensions in patients with AF. The patient population was composed of 100 patients referred for catheter ablation of AF (87 men, mean age 57 ± 12 years). AF was paroxysmal in 49 patients and persistent in 51. Each patient underwent computed tomography before catheter ablation, and LA volume was measured using the 2 methods. The mean LA volume measured using the multiple-slice technique was 136 ± 46 ml. According to the simpler estimation approach, the mean LA volume was 112 ± 41 ml. A close correlation was noted between atrial volumes determined using the 2 methods (r = 0.91, p <0.001). There was a mean underestimation of LA volume by the estimation technique of 17 ± 13%. In conclusion, the results of this study reveal that LA volume determined using an estimation approach correlates closely with true LA volume as determined using the gold-standard multiple-slice approach. This estimation approach underestimates true LA volume by approximately 20%.
AB - The success of catheter ablation of atrial fibrillation (AF) is highly dependent on a preprocedural assessment of the size and shape of the left atrium. The most precise method to determine left atrial (LA) volume using computed tomography requires manually tracing the LA area of each cross-sectional image. This is a labor-intensive and time-consuming technique. The purpose of this study was to compare LA volume derived using the "gold-standard" multiple-slice technique with LA volume estimated using 3 orthogonal LA dimensions in patients with AF. The patient population was composed of 100 patients referred for catheter ablation of AF (87 men, mean age 57 ± 12 years). AF was paroxysmal in 49 patients and persistent in 51. Each patient underwent computed tomography before catheter ablation, and LA volume was measured using the 2 methods. The mean LA volume measured using the multiple-slice technique was 136 ± 46 ml. According to the simpler estimation approach, the mean LA volume was 112 ± 41 ml. A close correlation was noted between atrial volumes determined using the 2 methods (r = 0.91, p <0.001). There was a mean underestimation of LA volume by the estimation technique of 17 ± 13%. In conclusion, the results of this study reveal that LA volume determined using an estimation approach correlates closely with true LA volume as determined using the gold-standard multiple-slice approach. This estimation approach underestimates true LA volume by approximately 20%.
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U2 - 10.1016/j.amjcard.2008.07.048
DO - 10.1016/j.amjcard.2008.07.048
M3 - Article
C2 - 19026316
AN - SCOPUS:56349122185
SN - 0002-9149
VL - 102
SP - 1567
EP - 1570
JO - American Journal of Cardiology
JF - American Journal of Cardiology
IS - 11
ER -