Validation and psychometric properties of the Asthma Control Questionnaire among children

Jessica M. Nguyen, Janet Teresa Holbrook, Christine Y. Wei, Lynn B. Gerald, W. Gerald Teague, Robert A Wise

Research output: Contribution to journalArticle

Abstract

Background The Asthma Control Questionnaire (ACQ) is a patient-centered tool for evaluating asthma control. It has been validated in adults, but not well-validated among children. Objective We evaluated the reliability, validity, and responsiveness to change of the ACQ for assessing asthma control in children ages 6 to 17 years. A threshold value for poor disease control and a minimally important difference were also determined. Methods Data from 305 asthmatic children enrolled in a clinical trial were examined. The ACQ was administered at 8 visits. We analyzed results for the combined age group and for the 6- to 11-year-old and 12- to 17-year-old age groups separately. Results Overall, the Cronbach α value (internal consistency) for the ACQ was 0.74 at baseline, and the intraclass correlation coefficient (test-retest reliability) for repeated questionnaires among stable patients was 0.53. The Pearson correlations between the ACQ and other asthma questionnaires were moderate to strong (-0.64 to -0.73). Mean ACQ scores were higher (worse) in patients whose peak flow decreased, who used more rescue medications, or who sought medical care for asthma than in patients who were stable (P

Original languageEnglish (US)
JournalThe Journal of Allergy and Clinical Immunology
Volume133
Issue number1
DOIs
StatePublished - Jan 2014

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Psychometrics
Asthma
Reproducibility of Results
Age Groups
Surveys and Questionnaires
Clinical Trials

Keywords

  • Asthma
  • asthma control
  • Asthma Control Questionnaire
  • minimally important difference
  • validity

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology

Cite this

Validation and psychometric properties of the Asthma Control Questionnaire among children. / Nguyen, Jessica M.; Holbrook, Janet Teresa; Wei, Christine Y.; Gerald, Lynn B.; Teague, W. Gerald; Wise, Robert A.

In: The Journal of Allergy and Clinical Immunology, Vol. 133, No. 1, 01.2014.

Research output: Contribution to journalArticle

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