Vagus Nerve Stimulator-Associated Sleep Disordered Breathing: Identification, Treatment, and Outcomes in a Pediatric Patient

Christopher M. Carosella, David F. Smith, Kathleen M. Sarber, Michele Turner, Thomas J. Dye

Research output: Contribution to journalArticlepeer-review

Abstract

Vagus nerve stimulator (VNS)-associated sleep disordered breathing (SDB) is a poorly understood side effect of VNS treatment. We present a patient with VNS-associated SDB who underwent sleep laboratory VNS titration, evaluation by drug-induced sleep endoscopy, and treatment including adenotonsillectomy and positive airway pressure therapy. This case is unique as it is the first to document, in real time, the inverse correlation of VNS current with airflow. This case offers unique insights into mechanisms and treatment of VNS-associated SDB, and a novel approach in its management. Most importantly, this case highlights the need for collaboration between physicians managing epilepsy with VNS and those managing sleep.

Original languageEnglish (US)
Article number1900069
Pages (from-to)31-35
Number of pages5
JournalJournal of Pediatric Neurology
Volume19
Issue number1
DOIs
StatePublished - Feb 1 2021
Externally publishedYes

Keywords

  • drug-induced sleep endoscopy
  • sleep disordered breathing
  • vagus nerve stimulator

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Clinical Neurology

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