Vagus nerve stimulation (VNS) for heart rate control using novel neural interfaces

Sanghoon Lee, Wendy Yen Xian Peh, Nitish V Thakor, Shih Cheng Yen, Chengkuo Lee

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

This paper demonstrates a novel neural interface for stimulation of a vagus nerve in rats. This novel design allows easy and quick implantation on very small nerves, so that it provides reliable stimulation in the vagus nerve. Vagus nerve stimulation (VNS) in rats is conducted using this neural interface to control heart rate while monitoring electrocardiogram (ECG). The heart rate is temporarily decreased while the stimulation and is recovered to baseline condition after the stimulation within certain ranges of stimulation parameters. This result shows that the proposed novel interface would be useful for peripheral nerve modulation in the future.

Original languageEnglish (US)
Title of host publicationTRANSDUCERS 2017 - 19th International Conference on Solid-State Sensors, Actuators and Microsystems
PublisherInstitute of Electrical and Electronics Engineers Inc.
Pages1730-1733
Number of pages4
ISBN (Electronic)9781538627310
DOIs
StatePublished - Jul 26 2017
Event19th International Conference on Solid-State Sensors, Actuators and Microsystems, TRANSDUCERS 2017 - Kaohsiung, Taiwan, Province of China
Duration: Jun 18 2017Jun 22 2017

Other

Other19th International Conference on Solid-State Sensors, Actuators and Microsystems, TRANSDUCERS 2017
CountryTaiwan, Province of China
CityKaohsiung
Period6/18/176/22/17

Keywords

  • heart rate
  • Neural interface
  • neuromodulation
  • vagus nerve

ASJC Scopus subject areas

  • Chemical Health and Safety
  • Instrumentation
  • Electrical and Electronic Engineering

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  • Cite this

    Lee, S., Peh, W. Y. X., Thakor, N. V., Yen, S. C., & Lee, C. (2017). Vagus nerve stimulation (VNS) for heart rate control using novel neural interfaces. In TRANSDUCERS 2017 - 19th International Conference on Solid-State Sensors, Actuators and Microsystems (pp. 1730-1733). [7994401] Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/TRANSDUCERS.2017.7994401