Vaccines for the prevention of HIV-1 disease

J. R. Mascola; G. J. Nabel

doi:10.1016/S0952-7915(00)00246-6

Vaccines for the prevention of HIV-1 disease

J. R. Mascola, G. J. Nabel

Research output: Contribution to journal › Article › peer-review

58 Scopus citations

Abstract

Clinical investigation in humans and experimental lentivirus infection in nonhuman primates have advanced our understanding of immune responses that control HIV-1 disease. Recently, immunization approaches in macaques have shown that the immune response can control viremia and improve clinical outcome. When such vaccine strategies are formulated to be similarly immunogenic in humans, they could form the basis for the development of candidate AIDS vaccines that would prevent infection, suppress progression to disease or reduce HIV-1 transmission in humans.

Original language	English (US)
Pages (from-to)	489-495
Number of pages	7
Journal	Current Opinion in Immunology
Volume	13
Issue number	4
DOIs	https://doi.org/10.1016/S0952-7915(00)00246-6
State	Published - Aug 1 2001
Externally published	Yes

ASJC Scopus subject areas

Immunology and Allergy
Immunology

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10.1016/S0952-7915(00)00246-6

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Vaccines for the prevention of HIV-1 disease

Abstract

ASJC Scopus subject areas

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