Vaccine effectiveness against DS-1-like rotavirus strains in infants with acute gastroenteritis, Malawi, 2013-2015

Khuzwayo C. Jere, Naor Bar-Zeev, Adams Chande, Aisleen Bennett, Louisa Pollock, Pedro F. Sanchez-Lopez, Osamu Nakagomi, Jacqueline E. Tate, Umesh D. Parashar, Robert S. Heyderman, Neil French, Miren Iturriza-Gomara, Nigel A. Cunliffe

Research output: Contribution to journalArticlepeer-review

Abstract

Atypical DS-1-like G1P[8] rotaviruses emerged in 2013 in Malawi after rotavirus vaccine introduction. Vaccine effectiveness among infants hospitalized with acute DS-1-like G1P[8] rotavirus gastroenteritis was 85.6% (95% CI 34.4%-96.8%). These findings suggest that vaccine provides protection against these strains despite their emergence coinciding with vaccine introduction.

Original languageEnglish (US)
Pages (from-to)1734-1737
Number of pages4
JournalEmerging infectious diseases
Volume25
Issue number9
DOIs
StatePublished - 2019

ASJC Scopus subject areas

  • Epidemiology
  • Microbiology (medical)
  • Infectious Diseases

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