Utility of three-phase skeletal scintigraphy in suspected osteomyelitis: concise communication

A. H. Maurer, D. C P Chen, E. E. Camargo, Dean Foster Wong, H. N. Wagner, P. O. Alderson

Research output: Contribution to journalArticle

Abstract

Three-phase skeletal scintigraphy, consisting of a radionuclide angiogram, an immediate postinjection 'blood-pool' image, and 2-3 hr delayed images, was performed on 98 patients with suspected osteomyelitis. This procedure was evaluated by first interpreting only the delayed images, next the combination of 'blood-pool' and delayed images, and finally the three-phase study. There was no change in the sensitivity (12/13 = 0.92) for detecting osteomyelitis, but the false-positive rate for osteomyelitis decreased from 0.25 (21/85) to 0.06 (5/85). In 21 of 64 patients (33%) with abnormal studies, the 'blood-pool' image and/or the radionuclide angiogram led to a more accurate scintigraphic diagnosis. In 12 patients (19%) the 'blood pool' alone was enough to achieve the correct final diagnosis and was used most often to identify noninfectious skeletal disease. In 9 patients (14%) the radionuclide angiogram was required for an accurate interpretation and was considered essential most often in cases of soft-tissue infection. Both radionuclide angiography and 'blood-pool' imaging appear to augment the specificity of skeletal scintigraphy in patients with suspected osteomyelitis.

Original languageEnglish (US)
Pages (from-to)941-949
Number of pages9
JournalJournal of Nuclear Medicine
Volume22
Issue number11
StatePublished - 1981
Externally publishedYes

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Osteomyelitis
Radionuclide Imaging
Communication
Radioisotopes
Angiography
Radionuclide Angiography
Soft Tissue Infections

ASJC Scopus subject areas

  • Radiological and Ultrasound Technology

Cite this

Maurer, A. H., Chen, D. C. P., Camargo, E. E., Wong, D. F., Wagner, H. N., & Alderson, P. O. (1981). Utility of three-phase skeletal scintigraphy in suspected osteomyelitis: concise communication. Journal of Nuclear Medicine, 22(11), 941-949.

Utility of three-phase skeletal scintigraphy in suspected osteomyelitis : concise communication. / Maurer, A. H.; Chen, D. C P; Camargo, E. E.; Wong, Dean Foster; Wagner, H. N.; Alderson, P. O.

In: Journal of Nuclear Medicine, Vol. 22, No. 11, 1981, p. 941-949.

Research output: Contribution to journalArticle

Maurer, AH, Chen, DCP, Camargo, EE, Wong, DF, Wagner, HN & Alderson, PO 1981, 'Utility of three-phase skeletal scintigraphy in suspected osteomyelitis: concise communication', Journal of Nuclear Medicine, vol. 22, no. 11, pp. 941-949.
Maurer, A. H. ; Chen, D. C P ; Camargo, E. E. ; Wong, Dean Foster ; Wagner, H. N. ; Alderson, P. O. / Utility of three-phase skeletal scintigraphy in suspected osteomyelitis : concise communication. In: Journal of Nuclear Medicine. 1981 ; Vol. 22, No. 11. pp. 941-949.
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