Utility of surface-supported bilayers in studies of transmembrane helix dimerization

Edwin Li, Mikhail Merzlyakov, Janice Lin, Peter Searson, Kalina Hristova

Research output: Contribution to journalArticlepeer-review

Abstract

This review focuses on the methods that are available to study transmembrane (TM) helix dimerization in membrane-like environments (either bacterial membranes or lipid bilayers, as mimics of the eukaryotic cellular membrane), with an emphasis on the utility of surface-supported bilayers in such studies.

Original languageEnglish (US)
Pages (from-to)53-60
Number of pages8
JournalJournal of Structural Biology
Volume168
Issue number1
DOIs
StatePublished - Oct 2009

Keywords

  • Supported bilayers
  • Thermodynamics
  • Transmembrane helix dimerization

ASJC Scopus subject areas

  • Structural Biology

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