USP2a Activation of MYC in Prostate Cancer

Research output: Contribution to journalArticle

Abstract

Ubiquitin-specific protease 2a, a deubiquitinating enzyme, elevates MYC levels in prostate cancer cells via its stabilization of MDM2, undermining p53 regulation of microRNAs that target MYC mRNA.

Original languageEnglish (US)
Pages (from-to)206-207
Number of pages2
JournalCancer Discovery
Volume2
Issue number3
DOIs
StatePublished - Mar 2012

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Ubiquitin-Specific Proteases
MicroRNAs
Prostatic Neoplasms
Messenger RNA
Deubiquitinating Enzymes

ASJC Scopus subject areas

  • Oncology

Cite this

USP2a Activation of MYC in Prostate Cancer. / Nelson, William G; Demarzo, Angelo Michael; Yegnasubramanian, S.

In: Cancer Discovery, Vol. 2, No. 3, 03.2012, p. 206-207.

Research output: Contribution to journalArticle

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