USP2a Activation of MYC in Prostate Cancer

William G. Nelson; Angelo M. De Marzo; Srinivasan Yegnasubramanian

doi:10.1158/2159-8290.CD-12-0027

USP2a Activation of MYC in Prostate Cancer

William G. Nelson, Angelo M. De Marzo, Srinivasan Yegnasubramanian

Research output: Contribution to journal › Article › peer-review

9 Scopus citations

Abstract

Ubiquitin-specific protease 2a, a deubiquitinating enzyme, elevates MYC levels in prostate cancer cells via its stabilization of MDM2, undermining p53 regulation of microRNAs that target MYC mRNA.

Original language	English (US)
Pages (from-to)	206-207
Number of pages	2
Journal	Cancer discovery
Volume	2
Issue number	3
DOIs	https://doi.org/10.1158/2159-8290.CD-12-0027
State	Published - Mar 2012

ASJC Scopus subject areas

Oncology

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@article{e5b41aa0a7044368a606c83539c02e5f,

title = "USP2a Activation of MYC in Prostate Cancer",

abstract = "Ubiquitin-specific protease 2a, a deubiquitinating enzyme, elevates MYC levels in prostate cancer cells via its stabilization of MDM2, undermining p53 regulation of microRNAs that target MYC mRNA.",

author = "Nelson, {William G.} and {De Marzo}, {Angelo M.} and Srinivasan Yegnasubramanian",

year = "2012",

month = mar,

doi = "10.1158/2159-8290.CD-12-0027",

language = "English (US)",

volume = "2",

pages = "206--207",

journal = "Cancer discovery",

issn = "2159-8274",

publisher = "American Association for Cancer Research Inc.",

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T1 - USP2a Activation of MYC in Prostate Cancer

AU - Nelson, William G.

AU - De Marzo, Angelo M.

AU - Yegnasubramanian, Srinivasan

PY - 2012/3

Y1 - 2012/3

N2 - Ubiquitin-specific protease 2a, a deubiquitinating enzyme, elevates MYC levels in prostate cancer cells via its stabilization of MDM2, undermining p53 regulation of microRNAs that target MYC mRNA.

AB - Ubiquitin-specific protease 2a, a deubiquitinating enzyme, elevates MYC levels in prostate cancer cells via its stabilization of MDM2, undermining p53 regulation of microRNAs that target MYC mRNA.

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JO - Cancer discovery

JF - Cancer discovery

IS - 3

ER -

USP2a Activation of MYC in Prostate Cancer

Abstract

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