Using Optimal Test Assembly Methods for Shortening Patient-Reported Outcome Measures: Development and Validation of the Cochin Hand Function Scale-6: A Scleroderma Patient-Centered Intervention Network Cohort Study

and the Scleroderma Patient-Centered Intervention Network Investigators, Susan J. Bartlett

Research output: Contribution to journalArticle

Abstract

Objective: To develop and validate a short form of the Cochin Hand Function Scale (CHFS), which measures hand disability, for use in systemic sclerosis, using objective criteria and reproducible techniques. Methods: Responses on the 18-item CHFS were obtained from English-speaking patients enrolled in the Scleroderma Patient-Centered Intervention Network Cohort. CHFS unidimensionality was verified using confirmatory factor analysis, and an item response theory model was fit to CHFS items. Optimal test assembly (OTA) methods identified a maximally precise short form for each possible form length between 1 and 17 items. The final short form selected was the form with the least number of items that maintained statistically equivalent convergent validity, compared to the full-length CHFS, with the Health Assessment Questionnaire (HAQ) disability index (DI) and the physical function domain of the 29-item Patient-Reported Outcomes Measurement Information System (PROMIS-29). Results: There were 601 patients included. A 6-item short form of the CHFS (CHFS-6) was selected. The CHFS-6 had a Cronbach's alpha of 0.93. Correlations of the CHFS-6 summed score with HAQ DI (r = 0.79) and PROMIS-29 physical function (r = −0.54) were statistically equivalent to the CHFS (r = 0.81 and r = −0.56). The correlation with the full CHFS was high (r = 0.98). Conclusion: The OTA procedure generated a valid short form of the CHFS with minimal loss of information compared to the full-length form. The OTA method used was based on objective, prespecified criteria, but should be further studied for viability as a general procedure for shortening patient-reported outcome measures in health research.

Original languageEnglish (US)
Pages (from-to)1704-1713
Number of pages10
JournalArthritis Care and Research
Volume68
Issue number11
DOIs
StatePublished - Nov 1 2016

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Cohort Studies
Hand
Patient Reported Outcome Measures
Health
Systemic Scleroderma
Information Systems
Statistical Factor Analysis

ASJC Scopus subject areas

  • Rheumatology

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Using Optimal Test Assembly Methods for Shortening Patient-Reported Outcome Measures : Development and Validation of the Cochin Hand Function Scale-6: A Scleroderma Patient-Centered Intervention Network Cohort Study. / and the Scleroderma Patient-Centered Intervention Network Investigators; Bartlett, Susan J.

In: Arthritis Care and Research, Vol. 68, No. 11, 01.11.2016, p. 1704-1713.

Research output: Contribution to journalArticle

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abstract = "Objective: To develop and validate a short form of the Cochin Hand Function Scale (CHFS), which measures hand disability, for use in systemic sclerosis, using objective criteria and reproducible techniques. Methods: Responses on the 18-item CHFS were obtained from English-speaking patients enrolled in the Scleroderma Patient-Centered Intervention Network Cohort. CHFS unidimensionality was verified using confirmatory factor analysis, and an item response theory model was fit to CHFS items. Optimal test assembly (OTA) methods identified a maximally precise short form for each possible form length between 1 and 17 items. The final short form selected was the form with the least number of items that maintained statistically equivalent convergent validity, compared to the full-length CHFS, with the Health Assessment Questionnaire (HAQ) disability index (DI) and the physical function domain of the 29-item Patient-Reported Outcomes Measurement Information System (PROMIS-29). Results: There were 601 patients included. A 6-item short form of the CHFS (CHFS-6) was selected. The CHFS-6 had a Cronbach's alpha of 0.93. Correlations of the CHFS-6 summed score with HAQ DI (r = 0.79) and PROMIS-29 physical function (r = −0.54) were statistically equivalent to the CHFS (r = 0.81 and r = −0.56). The correlation with the full CHFS was high (r = 0.98). Conclusion: The OTA procedure generated a valid short form of the CHFS with minimal loss of information compared to the full-length form. The OTA method used was based on objective, prespecified criteria, but should be further studied for viability as a general procedure for shortening patient-reported outcome measures in health research.",
author = "{and the Scleroderma Patient-Centered Intervention Network Investigators} and Levis, {Alexander W.} and Daphna Harel and Linda Kwakkenbos and Carrier, {Marie Eve} and Luc Mouthon and Bartlett, {Susan J.} and Bartlett, {Susan J.} and Dinesh Khanna and Malcarne, {Vanessa L.} and Maureen Sauve and {van den Ende}, {Cornelia H M} and Poole, {Janet L.} and Schouffoer, {Anne A.} and Joep Welling and Thombs, {Brett D.} and Murray Baron and Carolyn Ells and Yeona Jang and Steele, {Russell J.} and Dan Furst and Suzanne Kafaja and Karen Gottesman and {van den Hoogen}, Frank and Mayes, {Maureen D.} and Shervin Assassi and Nielson, {Warren R.} and Robert Riggs and Fredrick Wigley and Fredrick Wigley and Maia, {Angela Costa} and Catarina Leite and Ghassan El-Baalbaki and Jennifer Persmann and Kim Fligelstone and Catherine Fortune and Karen Nielsen and Tracy Frech and Dominique Godard and Marie Hudson and Genevieve Gyger and Delisle, {Vanessa C.} and Jewitt, {Lisa R.} and Brooke Levis and Katherine Milette and Ann Impens and Johnson, {Sindhu R.} and Kennedy, {Ann Tyrell} and Maggie Larche and Nader Khalidi and Carlo Marra",
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T2 - Development and Validation of the Cochin Hand Function Scale-6: A Scleroderma Patient-Centered Intervention Network Cohort Study

AU - and the Scleroderma Patient-Centered Intervention Network Investigators

AU - Levis, Alexander W.

AU - Harel, Daphna

AU - Kwakkenbos, Linda

AU - Carrier, Marie Eve

AU - Mouthon, Luc

AU - Bartlett, Susan J.

AU - Bartlett, Susan J.

AU - Khanna, Dinesh

AU - Malcarne, Vanessa L.

AU - Sauve, Maureen

AU - van den Ende, Cornelia H M

AU - Poole, Janet L.

AU - Schouffoer, Anne A.

AU - Welling, Joep

AU - Thombs, Brett D.

AU - Baron, Murray

AU - Ells, Carolyn

AU - Jang, Yeona

AU - Steele, Russell J.

AU - Furst, Dan

AU - Kafaja, Suzanne

AU - Gottesman, Karen

AU - van den Hoogen, Frank

AU - Mayes, Maureen D.

AU - Assassi, Shervin

AU - Nielson, Warren R.

AU - Riggs, Robert

AU - Wigley, Fredrick

AU - Wigley, Fredrick

AU - Maia, Angela Costa

AU - Leite, Catarina

AU - El-Baalbaki, Ghassan

AU - Persmann, Jennifer

AU - Fligelstone, Kim

AU - Fortune, Catherine

AU - Nielsen, Karen

AU - Frech, Tracy

AU - Godard, Dominique

AU - Hudson, Marie

AU - Gyger, Genevieve

AU - Delisle, Vanessa C.

AU - Jewitt, Lisa R.

AU - Levis, Brooke

AU - Milette, Katherine

AU - Impens, Ann

AU - Johnson, Sindhu R.

AU - Kennedy, Ann Tyrell

AU - Larche, Maggie

AU - Khalidi, Nader

AU - Marra, Carlo

PY - 2016/11/1

Y1 - 2016/11/1

N2 - Objective: To develop and validate a short form of the Cochin Hand Function Scale (CHFS), which measures hand disability, for use in systemic sclerosis, using objective criteria and reproducible techniques. Methods: Responses on the 18-item CHFS were obtained from English-speaking patients enrolled in the Scleroderma Patient-Centered Intervention Network Cohort. CHFS unidimensionality was verified using confirmatory factor analysis, and an item response theory model was fit to CHFS items. Optimal test assembly (OTA) methods identified a maximally precise short form for each possible form length between 1 and 17 items. The final short form selected was the form with the least number of items that maintained statistically equivalent convergent validity, compared to the full-length CHFS, with the Health Assessment Questionnaire (HAQ) disability index (DI) and the physical function domain of the 29-item Patient-Reported Outcomes Measurement Information System (PROMIS-29). Results: There were 601 patients included. A 6-item short form of the CHFS (CHFS-6) was selected. The CHFS-6 had a Cronbach's alpha of 0.93. Correlations of the CHFS-6 summed score with HAQ DI (r = 0.79) and PROMIS-29 physical function (r = −0.54) were statistically equivalent to the CHFS (r = 0.81 and r = −0.56). The correlation with the full CHFS was high (r = 0.98). Conclusion: The OTA procedure generated a valid short form of the CHFS with minimal loss of information compared to the full-length form. The OTA method used was based on objective, prespecified criteria, but should be further studied for viability as a general procedure for shortening patient-reported outcome measures in health research.

AB - Objective: To develop and validate a short form of the Cochin Hand Function Scale (CHFS), which measures hand disability, for use in systemic sclerosis, using objective criteria and reproducible techniques. Methods: Responses on the 18-item CHFS were obtained from English-speaking patients enrolled in the Scleroderma Patient-Centered Intervention Network Cohort. CHFS unidimensionality was verified using confirmatory factor analysis, and an item response theory model was fit to CHFS items. Optimal test assembly (OTA) methods identified a maximally precise short form for each possible form length between 1 and 17 items. The final short form selected was the form with the least number of items that maintained statistically equivalent convergent validity, compared to the full-length CHFS, with the Health Assessment Questionnaire (HAQ) disability index (DI) and the physical function domain of the 29-item Patient-Reported Outcomes Measurement Information System (PROMIS-29). Results: There were 601 patients included. A 6-item short form of the CHFS (CHFS-6) was selected. The CHFS-6 had a Cronbach's alpha of 0.93. Correlations of the CHFS-6 summed score with HAQ DI (r = 0.79) and PROMIS-29 physical function (r = −0.54) were statistically equivalent to the CHFS (r = 0.81 and r = −0.56). The correlation with the full CHFS was high (r = 0.98). Conclusion: The OTA procedure generated a valid short form of the CHFS with minimal loss of information compared to the full-length form. The OTA method used was based on objective, prespecified criteria, but should be further studied for viability as a general procedure for shortening patient-reported outcome measures in health research.

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