Using human induced pluripotent stem cells for modeling schizophrenia, a psychiatric disorder

Tarja A. Juopperi, Hongjun Song, Guo Li Ming

Research output: Contribution to journalArticlepeer-review

Abstract

There are inherent difficulties in developing well-defined experimental systems to study complex psychiatric disorders, such as schizophrenia. Advances have been made utilizing animal models; however, limitations in their ability to fully recapitulate the human disease exist. Induced pluripotent stem cells (iPSCs) derived from patients have the potential to revolutionize disease modeling for schizophrenia research and to provide a valuable resource for identification of crucial molecular pathways, biomarkers and for therapeutic drug screening.

Original languageEnglish (US)
JournalDrug Discovery Today: Disease Models
Volume9
Issue number4
DOIs
StatePublished - Dec 2012

ASJC Scopus subject areas

  • Drug Discovery
  • Molecular Medicine

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