Using contact patterns to inform HIV interventions in persons who inject drugs in northern Vietnam

M. Kumi Smith, Matthew Graham, Carl A. Latkin, Vivian L. Go

Research output: Contribution to journalArticlepeer-review

3 Scopus citations


Objectives: Population mixing patterns can greatly inform allocation of HIV prevention interventions such as treatment as prevention or preexposure prophylaxis. Characterizing contact patterns among subgroups can help identify the specific combinations of contact expected to result in the greatest number of new infections. Setting: Baseline data from an intervention to reduce HIV-related risk behaviors in male persons who inject drugs (PWID) in the Northern Vietnamese province of Thai Nguyen were used for the analysis. Methods: Egocentric network data were provided by PWID who reported any drug-injection equipment sharing in the previous 3 months. Age-dependent mixing was assessed to explore its epidemiological implications on risk of HIV transmission risk (among those HIVinfected) and HIV acquisition risk (among those not infected) in PWID. Results: A total of 1139 PWID collectively reported 2070 equipment-sharing partnerships in the previous 3 months. Mixing by age identified the 30-34 and 35-39 years age groups as the groups from whom the largest number of new infections was transmitted, making them primary targets for treatment as prevention. Among the uninfected, 25-29, 30-35, and 35-39 years age groups had the highest HIV acquisition rate, making them the primary targets for preexposure prophylaxis. Conclusions: Collection and analysis of contact patterns in PWID is feasible and can greatly inform infectious disease dynamics and targeting of appropriate interventions. Results presented also provide much needed empirical data on mixing to improve mathematical models of disease transmission in this population.

Original languageEnglish (US)
Pages (from-to)1-8
Number of pages8
JournalJournal of Acquired Immune Deficiency Syndromes
Issue number1
StatePublished - 2018


  • Contact mixing
  • HIV prevention
  • Persons who inject drugs
  • Preexposure prophylaxis
  • Treatment as prevention

ASJC Scopus subject areas

  • Infectious Diseases
  • Pharmacology (medical)


Dive into the research topics of 'Using contact patterns to inform HIV interventions in persons who inject drugs in northern Vietnam'. Together they form a unique fingerprint.

Cite this