User-friendly method for rapid brain and CSF volume calculation using transaxial MRI images

Gordon J. Harris; Edward H. Rhew; Thomas Noga; Godfrey D. Pearlson

doi:10.1016/0925-4927(91)90029-P

User-friendly method for rapid brain and CSF volume calculation using transaxial MRI images

Gordon J. Harris, Edward H. Rhew, Thomas Noga, Godfrey D. Pearlson

Research output: Contribution to journal › Article › peer-review

41 Scopus citations

Abstract

A reliable computer method was developed for straightforward, rapid determination of whole brain and cerebrospinal fluid (CSF) volumes from a set of contiguous transaxial magnetic resonance images. The semiautomatic algorithm used a threshold-guided edge follower. Subtraction of proton-weighted from T2-weighted images was used to highlight CSF. Phantom studies were used for validity assessment. Interrater and intrarater reliability and correlation with manual measurement were excellent. Percent CSF and brain volumes were determined for small groups of Alzheimer's disease, HIV seropositive, obsessive-compulsive disorder, and schizophrenic patients as well as for young and elderly normal controls.

Original language	English (US)
Pages (from-to)	61-68
Number of pages	8
Journal	Psychiatry Research: Neuroimaging
Volume	40
Issue number	1
DOIs	https://doi.org/10.1016/0925-4927(91)90029-P
State	Published - May 1991
Externally published	Yes

Keywords

Brain volume
cerebrospinal fluid percentage
computer methods
magnetic resonance imaging

ASJC Scopus subject areas

Neuroscience (miscellaneous)
Radiology Nuclear Medicine and imaging
Psychiatry and Mental health

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10.1016/0925-4927(91)90029-P

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AU - Rhew, Edward H.

AU - Noga, Thomas

AU - Pearlson, Godfrey D.

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User-friendly method for rapid brain and CSF volume calculation using transaxial MRI images

Abstract

Keywords

ASJC Scopus subject areas

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