TY - JOUR
T1 - Usefulness of measurement of the temporal stem on magnetic resonance imaging in the diagnosis of frontotemporal dementia
AU - Hayashida, Y.
AU - Hirai, T.
AU - Korogi, Y.
AU - Kimura, T.
AU - Ishizuka, K.
AU - Kawanaka, K.
AU - Yamura, M.
AU - Kitajima, M.
AU - Ikushima, I.
AU - Yamashita, Y.
PY - 2006/6/1
Y1 - 2006/6/1
N2 - Purpose: To investigate whether measurements of brain structures on routine magnetic resonance (MR) images can be used to distinguish between normal subjects and patients with frontotemporal dementia (FTD) or Alzheimer's disease (AD). Material and Methods: MRI studies were performed on 30 patients with dementia (FTD, n = 15; AD, n = 15) and 15 age-matched controls. Width measurements, obtained at the corpus callosum, the cingulate gyri, the hippocampi, and the temporal stem of the anterior temporal lobes, were compared among FTD and AD patients and control subjects on oblique-coronal T2-weighted images. Results: The width of the temporal stem was significantly narrower in FTD than in AD patients and control subjects (6.31.3mm, 7.81.1mm, and 8.20.9mm, respectively) ( P <5), although there was some overlapping between AD and FTD patients. All patients whose temporal stem width was <6 mm had FTD. While the width of the corpus callosum, cingulate gyri, and hippocampi was significantly narrower in patients with AD and FTD than in the controls, there was no significant difference between the AD and FTD patients. Conclusion: The width of the temporal stem was significantly narrower in patients with FTD than in those with AD and controls. The described measurements can easily be obtained and may be useful for the diagnosis of FTD.
AB - Purpose: To investigate whether measurements of brain structures on routine magnetic resonance (MR) images can be used to distinguish between normal subjects and patients with frontotemporal dementia (FTD) or Alzheimer's disease (AD). Material and Methods: MRI studies were performed on 30 patients with dementia (FTD, n = 15; AD, n = 15) and 15 age-matched controls. Width measurements, obtained at the corpus callosum, the cingulate gyri, the hippocampi, and the temporal stem of the anterior temporal lobes, were compared among FTD and AD patients and control subjects on oblique-coronal T2-weighted images. Results: The width of the temporal stem was significantly narrower in FTD than in AD patients and control subjects (6.31.3mm, 7.81.1mm, and 8.20.9mm, respectively) ( P <5), although there was some overlapping between AD and FTD patients. All patients whose temporal stem width was <6 mm had FTD. While the width of the corpus callosum, cingulate gyri, and hippocampi was significantly narrower in patients with AD and FTD than in the controls, there was no significant difference between the AD and FTD patients. Conclusion: The width of the temporal stem was significantly narrower in patients with FTD than in those with AD and controls. The described measurements can easily be obtained and may be useful for the diagnosis of FTD.
KW - Alzheimer's disease
KW - Dementia
KW - Frontotemporal dementia
KW - MRI
KW - Quantitative study
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U2 - 10.1080/02841850600776295
DO - 10.1080/02841850600776295
M3 - Article
C2 - 16875340
AN - SCOPUS:33745685742
SN - 0284-1851
VL - 47
SP - 603
EP - 608
JO - Acta Radiologica
JF - Acta Radiologica
IS - 6
ER -