Use of Tissue Doppler Imaging to Guide Tube Current Modulation in Cardiac Multidetector Computed Tomographic Angiography

Barbara Hesse, Ross T. Murphy, Gardar Sigurdsson, Marwan Nassif, Neil L. Greenberg, Chris Gring, Daniel Sauri, Milind Y. Desai, Mario J. Garcia

Research output: Contribution to journalArticle

Abstract

In multidetector computed tomographic coronary angiography, strategies to minimize effective radiation dose (ERD) are urgently needed. Prospective tube current modulation (TCM) allows a decrease in ERD, although it may limit reconstruction options. We sought to determine if tissue Doppler imaging (TDI) by echocardiography could predict an optimal phase for multidetector computed tomography and be used to guide TCM. Echocardiographic studies were performed in 94 patients immediately before multidetector computed tomography (83% men; mean 60 ± 11 years of age, mean body mass index 27.7 ± 4.1 kg/m2) and identified the most quiescent phase of the cardiac cycle within the atrioventricular groove. In 40 patients, prospective TCM was programmed according to TDI (TCMTDI group); 54 patients underwent multidetector computed tomography without TCM (no-TCM). In 25 patients assigned to the TCMTDI group, multidetector computed tomograms were correlated with invasive quantitative coronary angiograms to ensure maintenance of diagnostic accuracy. Optimal phase determined by TDI was 71 ± 11%, with a distinct bi-modal distribution. Compared with no-TCM, effective radiation dose was decreased by 42% in the TCMTDI group (6.6 ± 1.2 vs 11.4 ± 2.2 mSv, p 50% by multidetector computed tomography were 92%, 94%, 65%, and 99%, respectively. There was good correlation between quantitative coronary angiography and multidetector computed tomography for absolute degree of stenosis (r = 0.70, p

Original languageEnglish (US)
Pages (from-to)603-607
Number of pages5
JournalThe American Journal of Cardiology
Volume98
Issue number5
DOIs
Publication statusPublished - Sep 1 2006
Externally publishedYes

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ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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