Use of stored serum from Uganda for development and evaluation of a human immunodeficiency virus type 1 testing algorithm involving multiple rapid immunoassays

Darrell E. Singer, Noah Kiwanuka, David Serwadda, Fred Nalugoda, Linda Hird, Jamie Bulken-Hoover, Godfrey Kigozi, Jennifer A. Malia, Eva K. Calero, Warren Sateren, Merlin L. Robb, Fred Wabwire-Mangen, Maria Wawer, Ronald H. Gray, Nelson Sewankambo, Deborah L. Birx, Nelson L. Michael

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Abstract

We report the development and evaluation of a human immunodeficiency virus type 1 testing algorithm consisting of three rapid antibody detection tests. Stored serum samples from Uganda were utilized with a final algorithm sensitivity of 100% and a specificity of 98.9% (95% confidence interval, 98.6% to 99.3%).

Original languageEnglish (US)
Pages (from-to)5312-5315
Number of pages4
JournalJournal of clinical microbiology
Volume43
Issue number10
DOIs
StatePublished - Oct 1 2005

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ASJC Scopus subject areas

  • Microbiology (medical)

Cite this

Singer, D. E., Kiwanuka, N., Serwadda, D., Nalugoda, F., Hird, L., Bulken-Hoover, J., Kigozi, G., Malia, J. A., Calero, E. K., Sateren, W., Robb, M. L., Wabwire-Mangen, F., Wawer, M., Gray, R. H., Sewankambo, N., Birx, D. L., & Michael, N. L. (2005). Use of stored serum from Uganda for development and evaluation of a human immunodeficiency virus type 1 testing algorithm involving multiple rapid immunoassays. Journal of clinical microbiology, 43(10), 5312-5315. https://doi.org/10.1128/JCM.43.10.5312-5315.2005