Use of stored serum from Uganda for development and evaluation of a human immunodeficiency virus type 1 testing algorithm involving multiple rapid immunoassays

Darrell E. Singer, Noah Kiwanuka, David Serwadda, Fred Nalugoda, Linda Hird, Jamie Bulken-Hoover, Godfrey Kigozi, Jennifer A. Malia, Eva K. Calero, Warren Sateren, Merlin L. Robb, Fred Wabwire-Mangen, Maria Wawer, Ronald H. Gray, Nelson Sewankambo, Deborah L. Birx, Nelson L. Michael

Research output: Contribution to journalArticlepeer-review

Abstract

We report the development and evaluation of a human immunodeficiency virus type 1 testing algorithm consisting of three rapid antibody detection tests. Stored serum samples from Uganda were utilized with a final algorithm sensitivity of 100% and a specificity of 98.9% (95% confidence interval, 98.6% to 99.3%).

Original languageEnglish (US)
Pages (from-to)5312-5315
Number of pages4
JournalJournal of clinical microbiology
Volume43
Issue number10
DOIs
StatePublished - Oct 2005

ASJC Scopus subject areas

  • Microbiology (medical)

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