Use of neodymium yttrium aluminum garnet laser in long-term palliation of airway obstruction.

J. A. Quin, G. V. Letsou, L. T. Tanoue, R. A. Matthay, R. S. Higgins, J. C. Baldwin

Research output: Contribution to journalArticle

Abstract

Palliation of acute airway obstruction using the neodymium yttrium aluminum garnet (Nd-YAG) laser was studied in 54 patients who presented over a 42-month period to the Yale cardiothoracic surgery service. Thirty-seven patients had bronchogenic carcinoma; 27 had stage IIIB or IV disease. Nine patients had endobronchial metastases from a primary nonbronchogenic carcinoma. Eight patients had benign disease. A total of 109 Nd-YAG laser tumor ablations were performed. In addition, 32 patients underwent postoperative brachytherapy. Median survival for all patients was 12 months. Patients with bronchogenic carcinoma had a median survival of five months. Fifteen of 20 patients (75%) alive at the time of follow-up reported continued palliation as shown by an improved postoperative Karnofsky score. There was no survival benefit from Nd-YAG laser ablation of endobronchial bronchogenic carcinoma; however, the Nd-YAG laser provided good to excellent palliation in the majority of patients on long-term follow-up.

Original languageEnglish (US)
Pages (from-to)407-412
Number of pages6
JournalConnecticut medicine
Volume59
Issue number7
StatePublished - Jul 1995
Externally publishedYes

ASJC Scopus subject areas

  • Medicine(all)

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  • Cite this

    Quin, J. A., Letsou, G. V., Tanoue, L. T., Matthay, R. A., Higgins, R. S., & Baldwin, J. C. (1995). Use of neodymium yttrium aluminum garnet laser in long-term palliation of airway obstruction. Connecticut medicine, 59(7), 407-412.