Use of mass spectrometry-derived data to annotate nucleotide and protein sequence databases

Matthias Mann, Akhilesh Pandey

Research output: Contribution to journalArticlepeer-review

93 Scopus citations

Abstract

Mass spectrometry-based proteomic methodologies can be used to annotate both nucleotide and protein sequence databases. Because such data have to be derived from proteins, they can be used to identify coding regions of the genome as well as provide the complete primary sequence of proteins and their expression patterns and post-translational modifications.

Original languageEnglish (US)
Pages (from-to)54-61
Number of pages8
JournalTrends in Biochemical Sciences
Volume26
Issue number1
DOIs
StatePublished - Jan 1 2001

ASJC Scopus subject areas

  • Biochemistry

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