Use of functional analysis methodology in the evaluation of medication effects

Kimberly A. Crosland, Jennifer R. Zarcone, Steven E. Lindauer, Maria G. Valdovinos, Troy J. Zarcone, Jessica A. Hellings, Stephen R. Schroeder

Research output: Contribution to journalArticle

Abstract

The atypical antipsychotic medication risperidone was evaluated using a double-blind, placebo-controlled design in the treatment of destructive behavior in two individuals with autism. Premedication functional analyses indicated that destructive behavior was maintained by escape from demands, attention, or access to tangible items. For both individuals, destructive behavior during the demand condition was significantly reduced during the medication phases, whereas destructive behavior continued to occur to obtain tangible items (Reggie) and attention (Sean). In addition, there appeared to be a differential effect of the medication on self-injurious behavior (SIB) versus aggression for Sean. Results of the study demonstrate how functional analysis may provide information on those conditions and behaviors that are most likely to be affected by a specific medication.

Original languageEnglish (US)
Pages (from-to)271-279
Number of pages9
JournalJournal of Autism and Developmental Disorders
Volume33
Issue number3
DOIs
StatePublished - Jun 2003
Externally publishedYes

Fingerprint

Self-Injurious Behavior
Risperidone
Premedication
Autistic Disorder
Aggression
Antipsychotic Agents
Placebos

Keywords

  • Aggression
  • Autism
  • Functional analysis
  • Risperidone
  • Self-injurious behavior

ASJC Scopus subject areas

  • Psychology(all)
  • Developmental and Educational Psychology

Cite this

Crosland, K. A., Zarcone, J. R., Lindauer, S. E., Valdovinos, M. G., Zarcone, T. J., Hellings, J. A., & Schroeder, S. R. (2003). Use of functional analysis methodology in the evaluation of medication effects. Journal of Autism and Developmental Disorders, 33(3), 271-279. DOI: 10.1023/A:1024402500425

Use of functional analysis methodology in the evaluation of medication effects. / Crosland, Kimberly A.; Zarcone, Jennifer R.; Lindauer, Steven E.; Valdovinos, Maria G.; Zarcone, Troy J.; Hellings, Jessica A.; Schroeder, Stephen R.

In: Journal of Autism and Developmental Disorders, Vol. 33, No. 3, 06.2003, p. 271-279.

Research output: Contribution to journalArticle

Crosland, KA, Zarcone, JR, Lindauer, SE, Valdovinos, MG, Zarcone, TJ, Hellings, JA & Schroeder, SR 2003, 'Use of functional analysis methodology in the evaluation of medication effects' Journal of Autism and Developmental Disorders, vol 33, no. 3, pp. 271-279. DOI: 10.1023/A:1024402500425
Crosland KA, Zarcone JR, Lindauer SE, Valdovinos MG, Zarcone TJ, Hellings JA et al. Use of functional analysis methodology in the evaluation of medication effects. Journal of Autism and Developmental Disorders. 2003 Jun;33(3):271-279. Available from, DOI: 10.1023/A:1024402500425

Crosland, Kimberly A.; Zarcone, Jennifer R.; Lindauer, Steven E.; Valdovinos, Maria G.; Zarcone, Troy J.; Hellings, Jessica A.; Schroeder, Stephen R. / Use of functional analysis methodology in the evaluation of medication effects.

In: Journal of Autism and Developmental Disorders, Vol. 33, No. 3, 06.2003, p. 271-279.

Research output: Contribution to journalArticle

@article{38b138eaa00648ab9adea2623d09f530,
title = "Use of functional analysis methodology in the evaluation of medication effects",
abstract = "The atypical antipsychotic medication risperidone was evaluated using a double-blind, placebo-controlled design in the treatment of destructive behavior in two individuals with autism. Premedication functional analyses indicated that destructive behavior was maintained by escape from demands, attention, or access to tangible items. For both individuals, destructive behavior during the demand condition was significantly reduced during the medication phases, whereas destructive behavior continued to occur to obtain tangible items (Reggie) and attention (Sean). In addition, there appeared to be a differential effect of the medication on self-injurious behavior (SIB) versus aggression for Sean. Results of the study demonstrate how functional analysis may provide information on those conditions and behaviors that are most likely to be affected by a specific medication.",
keywords = "Aggression, Autism, Functional analysis, Risperidone, Self-injurious behavior",
author = "Crosland, {Kimberly A.} and Zarcone, {Jennifer R.} and Lindauer, {Steven E.} and Valdovinos, {Maria G.} and Zarcone, {Troy J.} and Hellings, {Jessica A.} and Schroeder, {Stephen R.}",
year = "2003",
month = "6",
doi = "10.1023/A:1024402500425",
volume = "33",
pages = "271--279",
journal = "Journal of Autism and Developmental Disorders",
issn = "0162-3257",
publisher = "Springer New York",
number = "3",

}

TY - JOUR

T1 - Use of functional analysis methodology in the evaluation of medication effects

AU - Crosland,Kimberly A.

AU - Zarcone,Jennifer R.

AU - Lindauer,Steven E.

AU - Valdovinos,Maria G.

AU - Zarcone,Troy J.

AU - Hellings,Jessica A.

AU - Schroeder,Stephen R.

PY - 2003/6

Y1 - 2003/6

N2 - The atypical antipsychotic medication risperidone was evaluated using a double-blind, placebo-controlled design in the treatment of destructive behavior in two individuals with autism. Premedication functional analyses indicated that destructive behavior was maintained by escape from demands, attention, or access to tangible items. For both individuals, destructive behavior during the demand condition was significantly reduced during the medication phases, whereas destructive behavior continued to occur to obtain tangible items (Reggie) and attention (Sean). In addition, there appeared to be a differential effect of the medication on self-injurious behavior (SIB) versus aggression for Sean. Results of the study demonstrate how functional analysis may provide information on those conditions and behaviors that are most likely to be affected by a specific medication.

AB - The atypical antipsychotic medication risperidone was evaluated using a double-blind, placebo-controlled design in the treatment of destructive behavior in two individuals with autism. Premedication functional analyses indicated that destructive behavior was maintained by escape from demands, attention, or access to tangible items. For both individuals, destructive behavior during the demand condition was significantly reduced during the medication phases, whereas destructive behavior continued to occur to obtain tangible items (Reggie) and attention (Sean). In addition, there appeared to be a differential effect of the medication on self-injurious behavior (SIB) versus aggression for Sean. Results of the study demonstrate how functional analysis may provide information on those conditions and behaviors that are most likely to be affected by a specific medication.

KW - Aggression

KW - Autism

KW - Functional analysis

KW - Risperidone

KW - Self-injurious behavior

UR - http://www.scopus.com/inward/record.url?scp=0042707915&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0042707915&partnerID=8YFLogxK

U2 - 10.1023/A:1024402500425

DO - 10.1023/A:1024402500425

M3 - Article

VL - 33

SP - 271

EP - 279

JO - Journal of Autism and Developmental Disorders

T2 - Journal of Autism and Developmental Disorders

JF - Journal of Autism and Developmental Disorders

SN - 0162-3257

IS - 3

ER -