Use of docetaxel (Taxotere®) in patients with paclitaxel (Taxol®) hypersensitivity

Chulso Moon, Claire F. Verschraegen, Michael Bevers, Ralph Freedman, Andrzej P. Kudelka, John J. Kavanagh

Research output: Contribution to journalArticlepeer-review

42 Scopus citations


Anaphylaxis or significant hypersensitivity reaction is one of the most catastrophic potential complications of chemotherapy. There is a 2-5% risk of hypersensitivity with paclitaxel, a commonly used chemotherapeutic agent for various cancers. Three patients, who developed hypersensitivity to paclitaxel infusion, received docetaxel without allergic reactions. Docetaxel may therefore be an alternative treatment for patients with paclitaxel hypersensitivity. (C) 2000 Lippincott Williams and Wilkins.

Original languageEnglish (US)
Pages (from-to)565-568
Number of pages4
JournalAnti-Cancer Drugs
Issue number7
StatePublished - 2000
Externally publishedYes


  • Allergic reactions
  • Ovarian neoplasms
  • Taxane

ASJC Scopus subject areas

  • Pharmacology
  • Cancer Research
  • Oncology


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