Use of dietary therapy for status epilepticus

Eric H. Kossoff, Rima Nabbout

Research output: Contribution to journalArticlepeer-review

Abstract

One of the newest and yet fastest growing indications for dietary therapy is the emergency treatment of refractory status epilepticus. Ten retrospective publications since 2008 have reported benefits in 32 children and adults, of whom 25 (78%) became seizure-free. Most of the patients who responded did so within 7 to 10 days of the initiation of nasogastrically administered ketogenic formulas. Encephalitis and febrile-illness related epilepsy syndrome causing status epilepticus highly refractory to antiepileptic drugs may be particularly amenable to dietary treatment. Prospective, multicenter studies are under way to help clarify who best will respond, how quickly, and the optimal diet duration after success.

Original languageEnglish (US)
Pages (from-to)1049-1051
Number of pages3
JournalJournal of child neurology
Volume28
Issue number8
DOIs
StatePublished - Aug 1 2013

Keywords

  • FIRES
  • emergency
  • epilepticus
  • ketogenic
  • refractory
  • status

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Clinical Neurology

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