Use of commercial enzyme immunoassays to detect antibodies to the herpes simplex virus type 2 glycoprotein g in a low-risk population in Hanoi, Vietnam

Thoai D. Ngo, Oliver B. Laeyendecker, Hanh La, Wayne Hogrefe, Rhoda Ashley Morrow, Thomas C Quinn

Research output: Contribution to journalArticle

Abstract

Sera from 1,238 Vietnamese women in Hanoi were tested for herpes simplex virus type 2 (HSV-2). HSV-2 prevalence was 2.0%. The Kalon and Biokit assays showed significantly higher concordance to Western blotting data than did the Focus assay (P <0.01). Screening by Focus and then retesting with Kalon/Biokit of positive samples can reduce falsely positive results significantly (P <0.01).

Original languageEnglish (US)
Pages (from-to)382-384
Number of pages3
JournalClinical and Vaccine Immunology
Volume15
Issue number2
DOIs
StatePublished - Feb 2008

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Human Herpesvirus 2
Vietnam
Immunoenzyme Techniques
Viruses
Assays
Glycoproteins
Antibodies
Enzymes
Population
Screening
Western Blotting
Serum

ASJC Scopus subject areas

  • Clinical Biochemistry
  • Immunology
  • Immunology and Allergy
  • Microbiology (medical)
  • Medicine(all)

Cite this

Use of commercial enzyme immunoassays to detect antibodies to the herpes simplex virus type 2 glycoprotein g in a low-risk population in Hanoi, Vietnam. / Ngo, Thoai D.; Laeyendecker, Oliver B.; La, Hanh; Hogrefe, Wayne; Morrow, Rhoda Ashley; Quinn, Thomas C.

In: Clinical and Vaccine Immunology, Vol. 15, No. 2, 02.2008, p. 382-384.

Research output: Contribution to journalArticle

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