Use of brief cognitive tests to identify individuals in the community with clinically diagnosed alzheimer's disease

Marilyn Albert, Laurel A. Smith, Paul A. Scherr, James O. Taylor, Denis A. Evans, H. Harris Funkenstein

Research output: Contribution to journalArticle

Abstract

Two brief screening tests, the Short Portable Mental Status Questionnaire (SPMSQ) and the East Boston Memory Test (EBMT), were included in a population questionnaire administered to 3,811 persons 65 years of age and older. A detailed clinical evaluation was then administered to 467 persons (drawn from high, medium and low performers on the EBMT) to determine who was cognitively impaired and the disorders that were responsible for that cognitive impairment. The results showed that the EBMT was better at enriching the population of the poor performance group with persons who had Alzheimer's disease (AD). It had a lower refusal rate among non-proxy respondents: 2% for the EBMT versus 9% for the SPMSQ. The sensitivity and positive predictive value were also higher for the EBMT than the SPMSQ when the diagnosis of interest was AD. However, there were persons with AD in all strata of performance on both the EBMT and the SPMSQ, emphasizing the importance of selecting persons from all performance strata in multistage community studies of AD.

Original languageEnglish (US)
Pages (from-to)167-178
Number of pages12
JournalInternational Journal of Neuroscience
Volume57
Issue number3-4
DOIs
StatePublished - 1991
Externally publishedYes

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Alzheimer Disease
Population
Surveys and Questionnaires

Keywords

  • Alzheimer's disease
  • Cognition
  • Elderly
  • Epidemiology
  • Screening tests

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

Use of brief cognitive tests to identify individuals in the community with clinically diagnosed alzheimer's disease. / Albert, Marilyn; Smith, Laurel A.; Scherr, Paul A.; Taylor, James O.; Evans, Denis A.; Funkenstein, H. Harris.

In: International Journal of Neuroscience, Vol. 57, No. 3-4, 1991, p. 167-178.

Research output: Contribution to journalArticle

Albert, Marilyn ; Smith, Laurel A. ; Scherr, Paul A. ; Taylor, James O. ; Evans, Denis A. ; Funkenstein, H. Harris. / Use of brief cognitive tests to identify individuals in the community with clinically diagnosed alzheimer's disease. In: International Journal of Neuroscience. 1991 ; Vol. 57, No. 3-4. pp. 167-178.
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