Use of applied biosystems 7900HT sequence detection system and taqman assay for detection of quinolone-resistant Neisseria gonorrhoeae

Julie Giles, Justin Hardick, Jeffrey Yuenger, Michael Dan, Karl Reich, Jonathan Mark Zenilman

Research output: Contribution to journalArticle

Abstract

Mutations in quinolone resistance-determining regions (QRDRs) have been associated with quinolone-resistant Neisseria gonorrhoeae (QRNG). Since diagnostic nucleic acid amplification tests for gonococci are now in frequent use, molecular detection of QRNG could facilitate surveillance in the absence of culture. Here we describe a real-time molecular assay for detecting QRDR mutations in gonococci.

Original languageEnglish (US)
Pages (from-to)3281-3283
Number of pages3
JournalJournal of Clinical Microbiology
Volume42
Issue number7
DOIs
StatePublished - Jul 2004

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Neisseria gonorrhoeae
Quinolones
Nucleic Acid Amplification Techniques
Mutation

ASJC Scopus subject areas

  • Microbiology (medical)
  • Microbiology

Cite this

Use of applied biosystems 7900HT sequence detection system and taqman assay for detection of quinolone-resistant Neisseria gonorrhoeae. / Giles, Julie; Hardick, Justin; Yuenger, Jeffrey; Dan, Michael; Reich, Karl; Zenilman, Jonathan Mark.

In: Journal of Clinical Microbiology, Vol. 42, No. 7, 07.2004, p. 3281-3283.

Research output: Contribution to journalArticle

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