USE OF ANTISERA FOR IDENTIFICATION OF ENTEROTOXIGENIC ESCHERICHIA COLI

Michael H. Merson, Robert E. Black, Roger J. Gross, Bernard Rowe, Imadul Huq, Abu Eusof

Research output: Contribution to journalArticlepeer-review

Abstract

The usual methods for identifying enterotoxigenic Escherichia coli (ETEC) strains involve testing for production of heat-labile and heat-stable enterotoxins. To simplify the identification of ETEC, antisera against common ETEC O serogroups were used to identify ETEC in the stools from 618 patients with acute diarrhœa and dehydration (≽5% loss of body-weight) receiving treatment at a hospital in Dacca, Bangladesh. Compared with enterotoxin testing the antisera had a sensitivity of 64%, a specificity of 96%, and a predictive accuracy of 89%. These antisera may be useful in the identification ETEC in clinical laboratories which are unable to perform toxin testing and should be evaluated in other geographical areas.

Original languageEnglish (US)
Pages (from-to)222-224
Number of pages3
JournalThe Lancet
Volume316
Issue number8188
DOIs
StatePublished - 1980
Externally publishedYes

ASJC Scopus subject areas

  • Medicine(all)

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