Use of Antidepressants in Medically Ill Older Patients

Harold G. Koenig; John C.S. Breitner

doi:10.1016/S0033-3182(90)72213-X

Use of Antidepressants in Medically Ill Older Patients

Harold G. Koenig, John C.S. Breitner

Research output: Contribution to journal › Review article › peer-review

Abstract

Major depression is common in older medical patients, and it can exert a deleterious effect on the treatment, course, and outcome of physical illnesses. Tricyclic or tetracyclic antidepressants (TCAs) and psychosocial interventions often play a role in the treatment of depressed medically ill patients, but well-founded doubts about the efficacy and the safety of TCAs in older, frail medical patients have developed. Based on a review of current knowledge about antidepressant use in these patients, the authors recommend the cautious use of TCAs in medically ill older patients until more data are available.

Original language	English (US)
Pages (from-to)	22-32
Number of pages	11
Journal	Psychosomatics
Volume	31
Issue number	1
DOIs	https://doi.org/10.1016/S0033-3182(90)72213-X
State	Published - Jan 1 1990
Externally published	Yes

ASJC Scopus subject areas

Arts and Humanities (miscellaneous)
Applied Psychology
Psychiatry and Mental health

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AB - Major depression is common in older medical patients, and it can exert a deleterious effect on the treatment, course, and outcome of physical illnesses. Tricyclic or tetracyclic antidepressants (TCAs) and psychosocial interventions often play a role in the treatment of depressed medically ill patients, but well-founded doubts about the efficacy and the safety of TCAs in older, frail medical patients have developed. Based on a review of current knowledge about antidepressant use in these patients, the authors recommend the cautious use of TCAs in medically ill older patients until more data are available.

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Use of Antidepressants in Medically Ill Older Patients

Abstract

ASJC Scopus subject areas

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