Use of a force-fiber technique for micromechanical measurements of the active force and stiffness of single heart cells

Research output: Contribution to conferencePaperpeer-review

Abstract

A description is presented of the development and use of a force-fiber technique to monitor the contracile and mechanical properties of single heart cells. The technique is implemented with an optical-fiber-based force probe coupled to a piezoelectric actuator. Measurements of cellular force with both deflection and null-balance feedback type systems are described. Potential applications of this technique include characterization of the rheological properties of single cells, measurements of cell adhesion, study of kinetics of crossbridge cycling, and excitation-contraction coupling.

Original languageEnglish (US)
Pages211-212
Number of pages2
StatePublished - Dec 1 1989
EventProceedings of the Fifteenth Annual Northeast Bioengineering Conference - Boston, MA, USA
Duration: Mar 27 1989Mar 28 1989

Other

OtherProceedings of the Fifteenth Annual Northeast Bioengineering Conference
CityBoston, MA, USA
Period3/27/893/28/89

ASJC Scopus subject areas

  • Bioengineering

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