Urticaria

Clive E.H. Grattan, Sarbjit S. Saini

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Urticaria is a mast cell-mediated disease characterized by hives, angioedema, or both. It can be spontaneous, inducible, or mixed. Chronic spontaneous urticaria may be autoimmune or idiopathic. The cause of inducible urticarias is unknown, although the eliciting trigger can be defined by provocation testing. Nonsedating H1-antihistamines should be used for all types of urticaria. Patients with chronic spontaneous urticaria not responding to H1-antihistamines can be considered for immunosuppressive drugs or omalizumab (anti-immunoglobulin E).

Original languageEnglish (US)
Title of host publicationAllergy Essentials
PublisherElsevier
Pages202-211
Number of pages10
ISBN (Electronic)9780323809122
ISBN (Print)9780323931212
DOIs
StatePublished - Jan 1 2022

Keywords

  • Angioedema
  • Bradykinin
  • Functional autoantibodies
  • H1-antihistamines
  • Histamine
  • Immunosuppressives
  • Omalizumab
  • Spontaneous and inducible urticarias

ASJC Scopus subject areas

  • General Medicine

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