Abstract
Urticaria is a mast cell-mediated disease characterized by hives, angioedema, or both. It can be spontaneous, inducible, or mixed. Chronic spontaneous urticaria may be autoimmune or idiopathic. The cause of inducible urticarias is unknown, although the eliciting trigger can be defined by provocation testing. Nonsedating H1-antihistamines should be used for all types of urticaria. Patients with chronic spontaneous urticaria not responding to H1-antihistamines can be considered for immunosuppressive drugs or omalizumab (anti-immunoglobulin E).
Original language | English (US) |
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Title of host publication | Allergy Essentials |
Publisher | Elsevier |
Pages | 202-211 |
Number of pages | 10 |
ISBN (Electronic) | 9780323809122 |
ISBN (Print) | 9780323931212 |
DOIs | |
State | Published - Jan 1 2022 |
Keywords
- Angioedema
- Bradykinin
- Functional autoantibodies
- H1-antihistamines
- Histamine
- Immunosuppressives
- Omalizumab
- Spontaneous and inducible urticarias
ASJC Scopus subject areas
- General Medicine