Urine nickel concentrations in nickel-exposed workers

E. J. Bernacki, G. E. Parsons, B. R. Roy, M. Mikac-Devic, C. D. Kennedy, F. W. Sunderman

Research output: Contribution to journalArticle


Electrothermal atomic absorption spectrometry was employed for analyses of nickel concentrations in urine samples from nickel-exposed workers in 10 occupational groups and from non-exposed workers in two control groups. Mean concentrations of nickel in urine were greatest in workers who were exposed to inhalation of aerosols of soluble nickel salts (e.g., workers in nickel plating operations and in an electrolytic nickel refinery). Less marked increases in urine nickel concentrations were found in groups of metal sprayers, nickel battery workers, bench mechanics and arc welders. No significant increases in mean concentration of nickel were found in urine samples from workers who performed grinding, buffing and polishing of nickel-containing alloys or workers in a coal gasification plant who employed Raney nickel as a hydrogenation catalyst. Measurements of nickel concentrations in urine are more sensitive and practical than measurement of serum nickel concentrations for evaluation of nickel exposures in industrial workers.

Original languageEnglish (US)
Pages (from-to)184-189
Number of pages6
JournalAnnals of Clinical and Laboratory Science
Issue number3
StatePublished - Dec 1 1978


ASJC Scopus subject areas

  • Microbiology
  • Immunology and Allergy
  • Pathology and Forensic Medicine
  • Immunology
  • Molecular Biology
  • Hematology
  • Clinical Biochemistry
  • Medical Laboratory Technology

Cite this

Bernacki, E. J., Parsons, G. E., Roy, B. R., Mikac-Devic, M., Kennedy, C. D., & Sunderman, F. W. (1978). Urine nickel concentrations in nickel-exposed workers. Annals of Clinical and Laboratory Science, 8(3), 184-189.