Urinary liver fatty acid-binding protein: Another novel biomarker of acute kidney injury

Blaithin A. McMahon; Patrick Thomas Murray

doi:10.1038/ki.2010.5

Urinary liver fatty acid-binding protein: Another novel biomarker of acute kidney injury

Blaithin A. McMahon, Patrick Thomas Murray

Research output: Contribution to journal › Comment/debate › peer-review

27 Scopus citations

Abstract

Liver fatty acid-binding protein (L-FABP) binds selectively to intracellular free unsaturated fatty acids and lipid peroxidation products during hypoxic tissue injury. Urinary L-FABP is a potential biomarker for the detection and assessment of acute kidney injury (AKI). Ferguson et al. have demonstrated in a cross-sectional study that urinary L-FABP is an excellent biomarker of AKI and may be useful in predicting dialysis-free survival. This study did not assess utility for early diagnosis of AKI.

Original language	English (US)
Pages (from-to)	657-659
Number of pages	3
Journal	Kidney International
Volume	77
Issue number	8
DOIs	https://doi.org/10.1038/ki.2010.5
State	Published - Apr 2010
Externally published	Yes

ASJC Scopus subject areas

Nephrology

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10.1038/ki.2010.5

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abstract = "Liver fatty acid-binding protein (L-FABP) binds selectively to intracellular free unsaturated fatty acids and lipid peroxidation products during hypoxic tissue injury. Urinary L-FABP is a potential biomarker for the detection and assessment of acute kidney injury (AKI). Ferguson et al. have demonstrated in a cross-sectional study that urinary L-FABP is an excellent biomarker of AKI and may be useful in predicting dialysis-free survival. This study did not assess utility for early diagnosis of AKI.",

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AB - Liver fatty acid-binding protein (L-FABP) binds selectively to intracellular free unsaturated fatty acids and lipid peroxidation products during hypoxic tissue injury. Urinary L-FABP is a potential biomarker for the detection and assessment of acute kidney injury (AKI). Ferguson et al. have demonstrated in a cross-sectional study that urinary L-FABP is an excellent biomarker of AKI and may be useful in predicting dialysis-free survival. This study did not assess utility for early diagnosis of AKI.

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Urinary liver fatty acid-binding protein: Another novel biomarker of acute kidney injury

Abstract

ASJC Scopus subject areas

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