Urinary liver fatty acid-binding protein: Another novel biomarker of acute kidney injury

Blaithin A. McMahon, Patrick Thomas Murray

Research output: Contribution to journalComment/debate

Abstract

Liver fatty acid-binding protein (L-FABP) binds selectively to intracellular free unsaturated fatty acids and lipid peroxidation products during hypoxic tissue injury. Urinary L-FABP is a potential biomarker for the detection and assessment of acute kidney injury (AKI). Ferguson et al. have demonstrated in a cross-sectional study that urinary L-FABP is an excellent biomarker of AKI and may be useful in predicting dialysis-free survival. This study did not assess utility for early diagnosis of AKI.

Original languageEnglish (US)
Pages (from-to)657-659
Number of pages3
JournalKidney International
Volume77
Issue number8
DOIs
StatePublished - Apr 2010
Externally publishedYes

ASJC Scopus subject areas

  • Nephrology

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